DIAGNOSIS OF PEDIATRIC OBSTRUCTIVE SLEEP APNEA

小儿阻塞性睡眠呼吸暂停的诊断

• 批准号: 2889584
• 负责人: NIRA A GOLDSTEIN
• 金额: $ 4.99万
• 依托单位: SUNY DOWNSTATE MEDICAL CENTER
• 依托单位国家: 美国
• 财政年份: 1998
• 资助国家: 美国
• 起止时间: 1998-07-01 至 2001-12-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/2889584
• 关键词: adenoidectomy; child (0-11); clinical research; diagnosis design /evaluation; diagnosis quality /standard; electrocardiography; human subject; longitudinal human study; lymphatic tissue; lymphatic tissue surgery; otorhinolaryngologic surgery; pediatrics; polysomnography; pulmonary circulation obstruction; radiography; respiratory disorder diagnosis; sleep apnea; statistics /biometry; ventricular hypertrophy

(Adapted from applicant's description): The investigator plans to prospectively evaluate 50 children with a clinical diagnosis of obstructive sleep apnea syndrome (OSAS) by a standardized history, physical examination, review of a tape recording of breathing during sleep, lateral neck radiograph to assess adenoid size, EKG to assess right ventricular hypertrophy, and behavioral assessment. A clinical assessment score will be assigned to each patient. Nocturnal polysomnography (NPSG) will then be used as the gold reference standard to determine the presence or absence of true sleep apnea. Children with a positive NPSG will undergo tonsillectomy and adenoidectomy. Children with negative NPSG will be randomized to undergo tonsillectomy and adenoidectomy or no surgery. All children will be reassessed in an identical fashion with follow-up NPSGs six months later.

（根据申请人描述改编）：研究者计划 前瞻性评估50名临床诊断为 阻塞性睡眠呼吸暂停综合征（OSAS）的标准化病史， 体格检查，检查呼吸过程中的磁带记录 睡眠，侧颈X线片评估腺样体大小，EKG评估 右心室肥大和行为评估 临床 评估分数将分配给每名患者。 夜间 多导睡眠图（NPSG）将被用作黄金参考标准 以确定是否存在真正的睡眠呼吸暂停。 儿童 阳性的NPSG将接受扁桃体切除术和腺样体切除术。 儿童 NPSG阴性的患者将随机接受扁桃体切除术， 要么做腺样体切除术要么不做手术 所有的孩子都将在一个 与6个月后随访NPSG的方式相同。