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MAINTENANCE & OPERATION OF A SYNTHETIC PEPTIDE FACILITY

MAINTENANCE & OPERATION OF A SYNTHETIC PEPTIDE FACILITY
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批准号：
2791838
负责人：
Richard Allen Houghten
金额：
$46.66万
依托单位：
MIXTURE SCIENCES, INC.
依托单位国家：
美国
项目类别：
财政年份：
1995
资助国家：
美国
项目状态：
已结题
起止时间：
1995-05-01 至 2000-04-30
来源：
https://reporter.nih.gov/project-details/2791838
关键词：
Plasmodium falciparum biomedical facility hepatitis B virus group peptide chemical synthesis protein purification protozoal antigen synthetic peptide tetanus toxin virus protein

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中文摘要
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英文摘要
The objective of this contract is to maintain and operate a Synthetic Peptide Facility capable of synthesizing gram-scale quantities (1-50 grams via single-batch or multiple small-batch preparation) of previously prepared peptides for toxicology studies, primate testing and clinical investigation as well as smaller quantities (5-100 milligrams) of new peptides for initial biological testing in small animals.
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Novel cyclic lipopeptides for treating gram negative bacterial infections
High throughput in vivo screening: translational generation of novel analgesics
High throughput in vivo screening: translational generation of novel analgesics
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