FINITE ELEMENT MODEL OF STABILIZED CANINE CERVICAL SPINE: TITANIUM IMPLANT

稳定犬颈椎的有限元模型：钛植入物

• 批准号: 6295219
• 负责人: RICHARD T HART
• 金额: $ 1.19万
• 依托单位: MELLON PITTS CORPORATION (MPC CORP)
• 依托单位国家: 美国
• 财政年份: 1998
• 资助国家: 美国
• 起止时间: 1998-09-30 至 1999-07-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/6295219
• 关键词: animal tissue; bioengineering /biomedical engineering; biomedical resource; nervous system; prosthesis; rehabilitation; skeletal system

This investigation intends to correlate titanium alloy plate strain and screw plate interface with titanium alloy metal ion release from posterior cervical spine implants in a dog model. It is believed that the magnitude of implant strain can influence the amount of metal released into the surrounding tissues and, in turn, that the concentration of material in the tissue will influence the implant's biological performance. Relative micromotion between various parts of the implant may accelerate the release of metal from the implant. As part of this investigation, a three-dimensional finite element model of the canine cervical spine segments(C3-C6), plates and screws will be developed. The model accuracy will be established through a convergence test, and it will be validated by modeling bench test loading schemes of ex-vivo specimens with strain gaged implants. The model will then be loaded as closely as possible to physiological conditions to depict the functional strain distributions. Contact stresses between the plate and bone and plate and screws will be examined. Finally, the results of the finite element model will be compared to the distributions of metal concentration found in the tissue.

本研究旨在将钛合金板材 应变螺纹板与钛合金金属离子释放的界面 取自狗模型的颈椎后部植入物。据信， 种植体应变的大小会影响金属的数量 释放到周围的组织中，进而， 材料在组织中的浓度会影响种植体的 生物学性能。关节各部分之间的相对微动 植入物可以加速金属从植入物中的释放。AS 作为本研究的一部分，三维有限元模型 在犬颈椎节段(C3-C6)中，钢板和螺钉将 被开发出来。模型的准确性将通过一个 收敛测试，并将通过模型台架测试进行验证 应变片植入体外标本的加载方案。这个 然后将模型加载到尽可能接近生理的位置 描述功能应变分布的条件。联系方式 钢板和骨之间的应力和钢板和螺丝之间的应力 检查过了。最后，有限元模型的结果将是 与发现的金属浓度分布相比， 组织。