DRUG ABUSE PREVENTION AMONG ADOLESCENT WOMEN

这一经修订的第一阶段可行性研究将审查与青少年妇女吸毒有关的社会心理因素。关于这些因素的数据将为制定基于计算机的互动干预措施提供信息。在六个月的时间里，第一阶段将实现三个目标。首先，我们将在纽约市的六个社区地点，对84名10 ~ 14岁的黑人、拉丁裔和白色青少年女性的药物滥用行为流行病学及其预防进行评估。第二，第一阶段将开发交互式软件原型，以减少这些年轻妇女使用毒品和其他物质的风险。第三，这项研究将试点测试的原型互动软件与270名黑人，拉丁裔，和白色的年轻妇女通过赞助的协作纽约市社区网站。在随机设计中，预试验涉及两组的适度临床试验。在被分配到计算机干预部门的地点，年轻妇女将与目标2中开发的原型软件互动。在对照点的年轻妇女将接受常规的药物认识干预。在干预前后，受试者将完成一系列结局指标。通过实现其目标，第一阶段将为第二阶段奠定基础。这项研究将充分开发一种互动式多媒体产品，以帮助年轻妇女减少吸毒风险。第二阶段将包括一项随机临床试验，在大纽约市不同社区环境的年轻妇女中测试开发的软件。如果第二阶段软件成功，第三阶段将把互动程序商业化，并向参与这一研发项目的学校、保健机构和社区机构传播。拟定商业应用：这项研究的数据将从经验上阐明年轻妇女使用毒品和其他物质的原因，以及计算机介导的干预措施如何帮助她们防止这种使用。通过明确设计的互动内容对年轻妇女进行干预，有望接触到预防药物滥用研究中迄今被忽视的高危人群并对其产生影响。

This revised Phase I feasibility study will examine psychosocial factors associated with drug use among adolescent women. Data on those factors will inform the development of an interactive computer-based intervention. Over the course of its 6 months, Phase I will accomplish three aims. First, we will assess the behavioral epidemiology of drug abuse and its prevention among a total sample of 84 Black, Latina, and white adolescent women, aged 10 to 14 years, from six community sites in New York City. Second, Phase I will develop a prototype version of interactive software to reduce the risks of drug and other substance use among those young women. Third, the study will pilot test the prototype interactive software with a sample of 270 Black, Latina, and white young women through the auspices of collaborating New York City community sites. In a randomized design, the pilot test involves a modest clinical trial with two arms. Young women in sites assigned to the computer intervention arm will interact with prototypic software developed in Aim 2. Young women in control sites will receive conventional drug awareness intervention. Before and after intervention, subjects will complete a battery of outcome measures. By meeting its aims, Phase I will lay a foundation for Phase II. That research will fully develop an interactive multimedia product to help young women reduce their risks for drug use. Phase II will include a randomized clinical trial to test the developed software with young women from various community settings in greater New York City. If Phase II software proves successful, Phase III will commercialize and disseminate the interactive program to schools and health care facilities and such community agencies as engaged in this R&D project. PROPOSED COMMERCIAL APPLICATION: Data from this study will shed empirical light on why young women use drugs and other substances and on how computer-mediated interventions can help them prevent that use. Intervening with young women via expressly designed and interactive content holds promise for reaching and impacting an at-risk population heretofore neglected in drug abuse prevention research.