课题基金 / 基金详情

FIBLAST TRAFERMIN IN TREATMENT OF INTERMITTENT CLAUDICATION

FIBLAST TRAFERMIN IN TREATMENT OF INTERMITTENT CLAUDICATION
FIBLAST TRAFERMIN 治疗间歇性跛行
批准号：
6281687
负责人：
SAMUEL WARD CASSCELLS
金额：
$1.36万
依托单位：
UNIVERSITY OF TEXAS HLTH SCI CTR HOUSTON
依托单位国家：
美国
项目类别：
财政年份：
1997
资助国家：
美国
项目状态：
已结题
起止时间：
1997-12-01 至 1998-11-30
来源：
https://reporter.nih.gov/project-details/6281687
关键词：
body movement cardiovascular disorder chemotherapy claudication clinical research exercise fibroblast growth factor functional ability human subject human therapy evaluation ischemia limbs

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英文摘要
Patients with intermittent claudication experience muscle aching or cramping during activity secondary to ischemia. The aim of this study is to determine if basic Fibroblast Growth Factor is effective in safely treating these patients. It will determine whether bFGF can increase blood flow in a sustained fashion due to an increase in vascular supply via new capillary formation and increased collateral flow. Parameters to be tested include exercise performance, functional status, improvement of hyperemic calf flow, and lower limb blood flow.
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