COMPOSITE CERAMIC/METAL WEAR COUPLES

本提案计划开发一种用于全关节的氮化硅陶瓷。 能与金属(钴铬、钴铬)连接的假体 组件。这是为了消除聚乙烯- 由于对聚乙烯的担忧，目前美国的金属磨损对 颗粒诱导的骨溶解。在另一种消除PE的方法中 磨屑和降低脆性失效的风险，一种金属/陶瓷 建议在髋臼衬垫(用于全髋关节)处 替代)由氮化硅基陶瓷制成，用于铰接 与传统的钴铬磁头进行对比。使用氮化硅的经验 其他领域的陶瓷显示出优异耐磨性的潜力。 生物医学应用中的抗药性。第一阶段将评估机械设备 热等静压对钴铬合金的性能和降低磨损率 模拟器测试。第二阶段将包括延长磨损测试，以及 设计和制造流程优化。 建议的商业应用： 一种先进的陶瓷衬里与衬垫的新颖组合 钴铬磁头会导致可以忽略不计的瓷器碎屑和骨溶解 植入失败。建议的材料将在HIPS中得到应用， 膝盖和其他关节的关节。

This proposal plans to develop a silicon nitride ceramic for total joint prostheses that would articulate against a metal (Cobalt-Chromium, Co-Cr) component. This is propose in an attempt to eliminate the polyethylene- metal wear couples currently in us due to concerns of polyethylene particle induced osteolysis. In an alternate approach to eliminating PE wear debris and lowering the risk of brittle failure, a metal/ceramic couple is proposed where the acetabular liner (for a total hip replacement) is made from a silicon nitride-based ceramic for articulating against a conventional Co-Cr head. Experience with silicon nitride ceramics in other fields points to the potential for superior wear resistance in biomedical applications. Phase I will assess the mechanical properties and demonstrate reduced wear rates against Co-Cr via hip simulator tests. Phase II will include extended wear tests along with design and manufacturing process optimization. PROPOSED COMMERCIAL APPLICATION: The novel combination of an advanced ceramic liner articulating against Co-Cr heads will lead to negligible ware debris and osteolysis mediated implant failures. The proposed materials will find applications in hips, knees and others articulating joints.