PEDIATRIC ONCOLOGY GROUP--MIDWEST CHILDREN'S CANCER CTR

中西部儿童癌症中心的主要目标是 降低儿童癌症的发病率和死亡率。这是 通过以下方式实现：1）提供尽可能好的患者护理（诊断 2）医疗和非医疗团体的教育， 不同类型、治疗和护理的可获得性 儿童癌症; 3）临床和实验室研究。调查人员 包括儿科肿瘤学，外科， 整形外科，神经外科，放射科，放射治疗， 病理学、神经学、心理学和护理学。所有新病人都是 在多学科肿瘤委员会讨论。然后孩子们 根据儿科肿瘤组（POG）或机构方案进行治疗。 定期分析和报告结果。 中西部儿童癌症中心参与 POG是：l）提高实现上述目标的概率 通过与其他机构合作，设计和执行 临床方案; 2）通过实验室评估 研究，肿瘤生物学方面，导致成功的， 治疗失败小儿肿瘤相对罕见。POG是 由50多个成员机构组成。通过集中资源， 对这些罕见肿瘤的生物学和治疗研究， 方便。类似的合作可以更快地开发新的 毒品此外，在共同环境中的参与有助于 在机构和调查人员之间传播信息。如果 所有患癌症的儿童都能得到最好的照顾， 死亡率将降到最低。 中西部儿童癌症中心一直是POG的主要贡献者 通过：1）患者招募; 2）POG方案协调; 3） 机构试点研究已推进到POG研究;以及4） 参与POG疾病和行政委员会。未来 在资助期内，我们会继续进行每一项活动。

The primary objective of the Midwest Children's Cancer Center is to reduce the incidence of and mortality from childhood cancers. This is approached by: 1) providing the best possible patient care (diagnostic and therapeutic; 2) education of medical and nonmedical groups as to the types of, treatments for, and availability of care for different childhood cancers; and 3) clinical and laboratory research. Investigators at the Cancer Center include specialists in pediatric oncology, surgery, orthopedic surgery, neurosurgery, radiology, radiation therapy, pathology, neurology, psychology and nursing. All new patients are discussed at a multidisciplinary Tumor Board. The children are then treated on Pediatric Oncology Group (POG) or institutional protocols. Results are analyzed and reported regularly. The purpose for the Midwest Children's Cancer Center's participation in POG are: l) to enhance the probability of achieving the above objectives by collaboration with other institutions in the design and execution of clinical protocols; and 2) to evaluate, through laboratory investigations, aspects of tumor biology which result in successful and unsuccessful therapy. Pediatric tumors are relatively rare. The POG is composed of more than 50 member institutions. By pooling resources, biologic and therapeutic studies on these uncommon tumors are facilitated. Similar collaboration permits more rapid development of new drugs. In addition, participation in a common milieu promotes dissemination of information between institutions and investigators. If all children with cancer receive the best possible care, morbidity and mortality will be minimized. The Midwest Children's Cancer Center has been a major contributor to POG by: 1) patient accrual; 2) coordination of POG protocols; 3) institutional pilot studies that were advanced to POG studies; and 4) participation in POG disease and administrative committees. In the next grant period we will continue each of these activities.