EATING DISORDERS IN YOUNG WOMEN--PREVALENCE AND RISK

描述（改编自申请人的摘要）：进食障碍 包括反复暴饮暴食（暴饮暴食症）构成了一个重要的 对年轻妇女的健康和心理调整造成风险。 电流 暴食症的知识是有限的a）虚拟排除 B）对妇女的研究很少 与频谱暴食症;和c）过度依赖的风险 对风险暴露进行回顾性评估的因素研究。 作为Aim I， 这项拟议中的研究将评估2,379名年轻的成年黑人和白色人 描述暴饮暴食症的范围。 使用 国家的最先进的情况下发现采访方法，我们将确定 神经性贪食症（BN）、暴食症（BED）及其 光谱变体（定义为满足除一个以外的所有要求标准 对于完整的综合征诊断）;我们还将确定当前Axis的存在 精神疾病。 确定BN、BED和 他们的频谱变体在这个社区为基础的样本，我们将比较 女性暴食症和健康对照的措施， 肥胖与心理调适。 种族和 进食障碍病例和对照的伴随变量将是 考察 研究的目的二是建立一个基于经验的， 暴食症风险的多因素模型，考虑了三个因素 主要风险领域：家庭背景，宪法的脆弱性， 个人脆弱性 为了评估风险暴露，将 在过去的一年中， 十年来，在这个特别好的队列中。 我们将 研究种族差异的相对贡献的风险因素， 暴饮暴食症的发展;确定风险的特异性;以及 比较完全综合征妇女与 暴食症 我们的研究应该能提供 通过确定高风险群体和风险， 可能会改变的因素。

DESCRIPTION (Adapted from the Applicant's Abstract): Eating disorders involving recurrent binge eating (binge eating disorders) pose a significant risk to the health and psychological adjustment of young women. Current knowledge of binge eating disorders is limited by a) the virtual exclusion of minority women from study samples; b) the paucity of studies of women with spectrum binge eating disorders; and c) the over reliance in risk factor studies on retrospective assessment of exposure to risk. As Aim I, the proposed study will assess a cohort of 2,379 young adult black and white women to describe the spectrum of binge eating disorders. Using state-of-the-art case finding interview methods, we will determine prevalence of bulimia nervosa (BN), binge eating disorder (BED), and their spectrum variants (defined as meeting all but one of the criteria required for full syndrome diagnosis); we will also identify presence of current Axis I psychiatric disorders. To determine clinical significance of BN, BED, and their spectrum variants in this community-based sample, we will compare women with a binge eating disorder and healthy controls on measures of obesity and psychological adjustment. The association of race and concomitant variables with eating disorder cases and controls will be examined. Aim II of the study is to develop an empirically based, multifactorial model of risk for binge eating disorders that considers three major risk domains: familial context, constitutional vulnerability, and personal vulnerability. For assessment of exposure to risk, data will be utilized that have been collected prospectively and longitudinally over a period of ten years in this exceptionally well-maintained cohort. We will examine race differences in the relative contribution of risk factors to the development of binge eating disorders; determine specificity of risk; and compare exposure to risk in women with full syndrome versus women with spectrum binge eating disorders. Our study should generate information relevant for primary prevention by identifying high risk groups and risk factors that may be amenable to change.