DECREASING ADVERSE EFFECTS OF FALSE POSITIVE MAMMOGRAMS

减少假阳性乳房 X 光检查的不良影响

• 批准号: 2895746
• 负责人: SUZANNE W FLETCHER
• 金额: $ 33.95万
• 依托单位: HARVARD PILGRIM HEALTH CARE, INC.
• 依托单位国家: 美国
• 财政年份: 1997
• 资助国家: 美国
• 起止时间: 1997-09-22 至 2001-06-30
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/2895746
• 关键词: anxiety; behavioral /social science research tag; bioimaging /biomedical imaging; clinical research; diagnosis quality /standard; female; health behavior; health care cost /financing; health care service utilization; human subject; interview; longitudinal human study; mammography; neoplasm /cancer education; outcomes research; psychological aspect of cancer; telecommunications; therapy compliance; videotape /videodisc

DESCRIPTION: False-positive mammogram readings, which account for more than 10 percent of all screening mammograms, cause long-lasting anxiety in women and are associated with low adherence to subsequent screening mammogram recommendations. The investigators propose a study to evaluate two strategies to reduce adverse psychosocial effects of false-positive mammograms in community women members of a large health maintenance organization in a Northeast urban area. A psychoeducational intervention, consisting of a videotape presentation and a pamphlet to explain the concept of a false-positive mammogram reading and how to cope with it will be developed and given to women at the time of their screening mammograms in eight radiology practices. It will be evaluated, along with a radiology system intervention to provide on-site readings and immediate follow-up investigations to women with abnormal readings. A factorial design, with four study groups will be used: Control, Education, Immediate Follow-up, and Both. Levels of anxiety and concern about breast cancer and mammography, adherence to subsequent screening mammography, health-care utilization in the 12 months after screening mammography, and daily functioning will be assessed in the women in each group, by telephone interviews at two weeks and three months after the screening mammogram, and by medical record review. Differences among the four groups will be sought, using the Impact of Event Scale and the Hopkins Symptom Checklist for levels of anxiety, and short-form General Health Survey for daily function. Psychological effects will be plotted over time, and effect modifiers will be sought to determine if the interventions affect women differentially. Feasibility and cost of both interventions will be determined and cost-effectiveness analyses will be performed. Because of high levels of anxiety about breast cancer and breast cancer screening among women in general, in a secondary study, the investigators will determine the same set of outcomes in two groups of women with normal mammogram readings: Control and Education. The study will determine whether simple strategies alleviate adverse psychosocial effects of an important breast cancer screening procedure that more than 25 million American women receive each year.

描述：假阳性乳房X光片读数， 10%的乳房X光检查会导致女性长期焦虑 并且与对随后的筛查性乳房X光检查的低依从性相关 建议. 研究人员提出了一项研究， 减少假阳性的不良心理社会影响的战略 乳房X光检查在社区妇女成员中的一个大的健康维护 东北地区的一个城市。 心理教育干预， 包括一盘录像带和一本小册子来解释这个概念 假阳性乳房X光片阅读以及如何科普它将是 在妇女进行乳房X光检查时， 八个放射科诊所 它将被评估，沿着放射学检查 系统干预，提供现场读数和即时跟进 对读数异常的妇女进行调查。 因子设计， 将使用四个研究组：对照组、教育组、立即随访组， 和两者。 对乳腺癌的焦虑和担忧程度， 乳房X光检查，坚持随后的筛查性乳房X光检查，保健 筛查乳腺X线摄影后12个月内的使用率，以及每日 将通过电话评估每组妇女的功能 在筛查乳房X光检查后两周和三个月进行访谈， 通过医疗记录审查。 将寻求这四个群体之间的差异， 使用事件影响量表和霍普金斯症状自评量表 焦虑和日常功能的简短一般健康调查。 心理效果将随时间绘制，效果修改器将 应设法确定这些干预措施是否对妇女产生不同的影响。 将确定这两种干预措施的可行性和成本， 将进行成本效益分析。 由于高水平的 2005年女性对乳腺癌和乳腺癌筛查的焦虑 一般而言，在二次研究中，研究者将确定相同的数据集， 两组乳腺X线检查结果正常的妇女的结果：对照组 和教育 这项研究将确定简单的策略是否能减轻 一项重要的乳腺癌筛查对心理社会的不良影响 每年有超过2500万美国妇女接受这种手术。