CONFERENCE: MOLECULAR CONCEPTS IN RADIATION ONCOLOGY

1999年戈登分子概念研究会议(GRC) 放射肿瘤学将在加利福尼亚州文图拉的假日酒店举行， 1999年1月31日至2月5日。这是第二次与以下主题相关的会议 这一专题与1997年6月的第一个专题非常受欢迎。这 提案用于部分支持受邀人员的旅费和费用 参与者。 在理解方面继续取得非常迅速的进展 细胞对电离辐射(IR)的反应包括： 识别参与DNA损伤识别和修复的分子， 损伤激活的信号转导通路的作用 DNA和包括细胞膜在内的其他大分子，以及 细胞所使用的分子在延缓细胞周期进程中的作用 并启动细胞凋亡。基因组中涉及的分子过程 不稳定性和肿瘤微环境影响，包括应激 反应，也正在被阐明。关于分子的知识 对IR的反应增强了对正常组织损伤和 正在引领着新的治疗方法的发展 诊所。 GRC将汇集基础科学家、翻译科学家和临床科学家 讨论这些新的发展并探索它们的潜力 放射肿瘤学治疗癌症的研究进展。

The 1999 Gordon Research Conference (GRC) on Molecular Concepts in Radiation Oncology will be held at the Holiday Inn, Ventura, California, January 31- February 5, 1999. This is the second conference related to this topic with the first, in June 1997, being very well received. This proposal is for partial support for travel and expenses for invited participants. There continues to be extraordinarily rapid progress in understanding the response of the cell to ionizing radiation (IR) including: identifying the molecules involved in DNA damage recognition and repair, the role of signal transduction pathways that are activated by damage to DNA and other macromolecules including the cell membrane, and the role of the molecules used by the cell to delay cell cycle progression and initiate apoptosis. The molecular processes involved in genomic instability and tumor microenvironmental effects, including the stress response, are also being elucidated. The knowledge of the molecular response to IR is enhancing the understanding normal tissue injury and is leading to the development of novel therapeutic approaches in the clinic. The GRC will bring together basic, translational and clinical scientists to discuss these new developments and to explore their potential for advances in cancer treatment by radiation oncology.