BIOLOGY AND EXPERIMENTAL THERAPY OF BREAST CANCER

这项来自人文部的多学科研究计划 肿瘤学和威斯康星临床癌症中心利用这两个实验室 和临床计划，以实现提高治疗效果的目标 在疾病的所有阶段都有效。个别项目有 目的：1)建立乳腺癌特异性克隆检测方法 评价其对乳腺癌治疗的预测效果；2)改进 原发乳腺癌的整体治疗；3)了解基础知识 激素依赖的生物学及其作用机制的确定 雌激素和抗雌激素在乳腺癌治疗中的应用； 检测人类乳房细胞中的特定基因突变；5)使用 生物统计支持和基于计算机的数据管理，以促进 研究；以及6)提供适当的行政支持，使 研究。

This multidisciplinary research program from the Department of Human Oncology and the Wisconsin Clinical Cancer Center utilizes both laboratory and clinical programs to achieve the goal of improving therapeutic effectiveness at all stages of the disease. Individual projects are directed at: 1) developing a breast cancer specific clonal assay and evaluating its predictive efficacy for breast cancer therapy; 2) improving the overall treatment of primary breast cancer; 3) understanding the basic biology of hormone dependency and determining the mechanism of action of estrogens and antiestrogens used in the treatment of breast cancer; 4) examining specific locus mutagenesis in human breast cells; 5) use of biostatistical support and computer-based data management to facilitate research; and 6) providing appropriate administrative support to enable the research.