Novel mechanisms integrating the central and autonomic nervous system

整合中枢和自主神经系统的新机制

• 批准号: DP180103219
• 负责人: A/Prof Quenten Schwarz
• 金额: $ 26.4万
• 依托单位: University of South Australia
• 依托单位国家: 澳大利亚
• 项目类别: Discovery Projects
• 财政年份: 2018
• 资助国家: 澳大利亚
• 起止时间: 2018-01-01 至 2020-12-31
• 项目状态: 已结题
• 来源: https://dataportal.arc.gov.au/RGS/Web/Grants/DP180103219
• 关键词: Novel; mechanisms; integrating; central; autonomic

This project aims to define molecular mechanisms controlling the exquisite connectivity of neurons in different parts of the body. The ability of higher-vertebrates to respond to different environmental conditions is essential for life, evolution, health, reproduction and growth, and is reliant on the autonomic nervous system. However, how the autonomic nervous system is integrated with the central nervous system to control holistic physiological responses is largely unknown. By deciphering how neural networks are formed this project aims to provide broad biological insight to wiring of the entire nervous system which is likely to have significant implications for the formation of synthetic neural networks and for regeneration.

该项目旨在确定控制身体不同部位神经元精致连接的分子机制。高等脊椎动物对不同环境条件的反应能力对生命、进化、健康、繁殖和生长至关重要，并且依赖于自主神经系统。然而，自主神经系统如何与中枢神经系统相结合来控制整体生理反应在很大程度上是未知的。通过破译神经网络是如何形成的，该项目旨在为整个神经系统的布线提供广泛的生物学见解，这可能对合成神经网络的形成和再生产生重大影响。