CANCER RESEARCH CENTER

癌症研究中心

• 批准号: 3101825
• 负责人: ROBERT R WAGNER
• 金额: $ 64.28万
• 依托单位: UNIVERSITY OF VIRGINIA
• 依托单位国家: 美国
• 财政年份: 1987
• 资助国家: 美国
• 起止时间: 1987-07-01 至 1994-07-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/3101825
• 关键词: biomedical facility; cellular oncology

The continuing objectives of this amended grant are to promote and augment the development of a basic cancer research center devoted to collaborative, innovative investigation at a fundamental level with an eye to future clinical cancer research endeavors. Scientists from different backgrounds and different academic departments are coordinating their on-going research efforts to mount a frontal attack on the various aspects of cancer research. Efforts will be concentrated in five research programs, each under the direction of a senior scientist, as follows: Program 1: Cellular Functions and Growth Control: Intracellular Mechanisms; Program 2; Cell structure, Growth and Regulation; Program 3: Control of Hematopoietic Cell Differentiation and Proliferation; Program 4: Growth and Differentiation of Mammalian Endocrine Cells; Program 5: Antigen Recognition and Cellular Activation in Immune Responses. Most of the scientists in each of these five programs have had longstanding collaborative research programs. It is our intention to expand these efforts of existing staff investigators and to recruit new investigators who can bring fresh ideas and new techniques into these collaborative research efforts. The Cancer Research Center will provide the environment for interplay among staff investigators of all five programs, who will be using advanced central research facilities. The NCI Cancer Centers staff has justifiably ruled that we are a Basic Cancer Research Center, but with their encouragement, we shall continue independent development of clinical cancer research initiatives promoted entirely by local funds. Accomplishments during the first three years of CCSG support include: increase in Staff Investigators from 60 to 80; recruitment of seven New Investigators; doubling use by Staff Investigators of Shared Core Research Facilities; renewal of one and acquisition of another program-project grant; acquisition and renovation of new Cancer Center laboratories; development of a new Program in Cancer Immunology; and major expansion of Cancer Center seminars and symposia for greater interaction among Staff Investigators.

这项修订后的赠款的持续目标是促进和 加强基础癌症研究中心的发展，致力于 在基础层面进行协作、创新的调查 着眼于未来的临床癌症研究工作。 科学家们来自 不同背景、不同学术部门正在协调 他们正在进行的研究工作对各种 癌症研究的各个方面。 重点在五个方面发力 研究项目，每个项目都在一位资深科学家的指导下，例如 如下： 程序 1：细胞功能和生长控制：细胞内 机制；计划2；细胞结构、生长和调节；方案3： 造血细胞分化和增殖的控制；程序 4：哺乳动物内分泌细胞的生长和分化；方案5： 免疫反应中的抗原识别和细胞激活。 最多 这五个项目中每一个项目的科学家都拥有长期的 合作研究计划。 我们的目的是扩大这些 现有工作人员调查员的努力以及招募新调查员的努力 谁可以将新的想法和新技术带入这些协作中 研究工作。 癌症研究中心将提供 所有五个项目的研究人员之间相互作用的环境， 谁将使用先进的中央研究设施。 美国国家癌症研究所癌症 中心工作人员有理由裁定我们是基础癌症研究中心 中心，但在他们的鼓励下，我们将继续独立 完全由以下机构推动的临床癌症研究计划的发展 地方资金。 CCSG 支持的头三年取得的成就包括： 调查员人数从 60 人增加到 80 人；招募七名新人 调查员；工作人员调查员对共享核心的使用加倍 研究设施；更新一项并收购另一项 方案项目补助金；收购和改造新癌症中心 实验室；开发癌症免疫学新项目；和 癌症中心研讨会和专题讨论会的重大扩展 工作人员调查员之间的互动。