CANCER RESEARCH CENTER

这一修订赠款的持续目标是促进和 加强基础癌症研究中心的发展， 合作，创新的调查在一个基本的水平， 着眼于未来的临床癌症研究工作。 的科学家 不同的背景和不同的学术部门正在协调 他们正在进行的研究工作，以发动正面攻击的各种 癌症研究方面。 努力将集中在五个方面 研究计划，每一个在一个资深科学家的指导下，作为 程序1：细胞功能和生长控制：细胞内 机制;程序2;细胞结构、生长和调节;程序3： 造血细胞分化和增殖的控制;程序 4：哺乳动物内分泌细胞的生长和分化;程序5： 免疫应答中的抗原识别和细胞活化。 最 在这五个项目中， 合作研究项目。 我们打算扩大这些 现有调查员工作人员的努力和征聘新的调查员 他们可以将新的想法和新的技术带入这些合作项目中， 研究工作。 癌症研究中心将提供 所有五个项目的工作人员调查员之间相互作用的环境， 他们将使用先进的中央研究设施 NCI癌症 中心的工作人员已经合理地裁定，我们是一个基本的癌症研究 中心，但在他们的鼓励下，我们将继续独立 发展临床癌症研究计划，完全由 地方资金。 在CCSG支持的头三年中取得的成就包括： 工作人员调查员从60名增加到80名;征聘7名新 调查员;工作人员调查员加倍使用共享核心 研究设施;更新一个和收购另一个 方案-项目赠款;购置和翻修新的癌症中心 实验室;开发一个新的癌症免疫学计划;以及 癌症中心研讨会和专题讨论会的重大扩展， 研究人员之间的互动。

The continuing objectives of this amended grant are to promote and augment the development of a basic cancer research center devoted to collaborative, innovative investigation at a fundamental level with an eye to future clinical cancer research endeavors. Scientists from different backgrounds and different academic departments are coordinating their on-going research efforts to mount a frontal attack on the various aspects of cancer research. Efforts will be concentrated in five research programs, each under the direction of a senior scientist, as follows: Program 1: Cellular Functions and Growth Control: Intracellular Mechanisms; Program 2; Cell structure, Growth and Regulation; Program 3: Control of Hematopoietic Cell Differentiation and Proliferation; Program 4: Growth and Differentiation of Mammalian Endocrine Cells; Program 5: Antigen Recognition and Cellular Activation in Immune Responses. Most of the scientists in each of these five programs have had longstanding collaborative research programs. It is our intention to expand these efforts of existing staff investigators and to recruit new investigators who can bring fresh ideas and new techniques into these collaborative research efforts. The Cancer Research Center will provide the environment for interplay among staff investigators of all five programs, who will be using advanced central research facilities. The NCI Cancer Centers staff has justifiably ruled that we are a Basic Cancer Research Center, but with their encouragement, we shall continue independent development of clinical cancer research initiatives promoted entirely by local funds. Accomplishments during the first three years of CCSG support include: increase in Staff Investigators from 60 to 80; recruitment of seven New Investigators; doubling use by Staff Investigators of Shared Core Research Facilities; renewal of one and acquisition of another program-project grant; acquisition and renovation of new Cancer Center laboratories; development of a new Program in Cancer Immunology; and major expansion of Cancer Center seminars and symposia for greater interaction among Staff Investigators.