CLINICAL RESEARCH CENTER: STUDY OF CHILDHOOD PSYCHOSIS

临床研究中心：儿童精神病研究

• 批准号: 3106970
• 负责人: PETER E TANGUAY
• 金额: $ 19.38万
• 依托单位: UNIVERSITY OF CALIFORNIA LOS ANGELES
• 依托单位国家: 美国
• 财政年份: 1977
• 资助国家: 美国
• 起止时间: 1977-09-29 至 1987-01-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/3106970
• 关键词: attention; automated medical record system; behavior disorders; behavior test; behavioral genetics; child behavior disorders; disease /disorder classification; early infantile autism; human subject; language disorders; longitudinal human study; mental disorder diagnosis; mental health epidemiology; middle childhood (6-11); neural information processing; neuropsychology; organic brain syndrome; preschool child (1-5); psychophysiology; schizoid personality; urinalysis

The Child Psychiatry Clinical Research Center is an assembly of scientists engaged in comprehensive, multidisciplinary, and interactive research into the etiology, prevention and treatment of serious psychopathology in childhood. Diagnostic categories under study are early infantile autism, childhood onset pervasive disorder and attention deficit disorder (ADD). Epidemiological, genetic, neuropharmacological electrophysiological, neurobehavioral, linguistic, cognitive, and sociobehavioral studies are carried out in the Center. The Center also serves as an interdisciplinary research trainng resource for MD's and Phd's, and as a community resource for information and consultation for the above disorders. Research projects in 1984 include: 1. A multi-laboratory study of the neurobehavioral and electrophysiological correlates of information processing deficits in schizophrenic, schizotypal and ADD subjects. 2. A multilaboratory study of the longitudinal course of psychosis in children, with a particular focus on schizophrenia, and upon autistic children who later become schizophrenic. These studies include investigation of the incidence of mental illness in the families of the children, and of the effect of family social factors as predictors of outcome. 3. A study of the use of structured interviews for diagnosis of serious psychopathology in pre-school and school age children. 4. A group study of early language and cognitive development in children with infantile autism and childhood onset pervasive development disorder. 5. Numerous single laboratory studies including: study of hemispheric specialization for semantic memory; study of the prosodic and information processing capacities of autistic and schizophrenic children; development of a 'thought disorder index' for use with children; study of genetic and immuno-hematological factors in infantile autism; and study of the 'startle response' as a measure of brain-stem processing in autistic children. Among new projects under development at present is a multi-laboratory study of a new system of classification of serious psychopathology in children. It is intended that this project will become a particular focus of research during the renewal period.

儿童精神病学临床研究中心是一个由科学家组成的 从事全面的，多学科的，互动的研究， 严重精神病的病因、防治 童年. 正在研究的诊断类别是早期婴儿自闭症， 儿童期发作的广泛性障碍和注意力缺陷障碍（ADD）。 流行病学，遗传学，神经药理学，电生理学， 神经行为、语言、认知和社会行为研究是 在中心进行。 该中心还作为一个跨学科的 研究培训资源的MD和博士的，并作为一个社区资源 以获取有关上述疾病的资料及咨询。 1984年的研究项目包括： 1.神经行为和电生理的多实验室研究 典型精神分裂症患者信息处理缺陷的相关因素 添加主题 2.精神病纵向病程的多实验室研究 儿童，特别关注精神分裂症，以及自闭症 后来患上精神分裂症的孩子 这些研究包括 2002年北京市部分老年人家庭精神病发病率调查 儿童，以及家庭社会因素的影响作为预测因素， 结果。 3.结构化访谈在严重精神分裂症诊断中的应用研究 学龄前和学龄儿童的精神病理学。 4.儿童早期语言和认知发展的团体研究 患有自闭症和儿童期广泛性发育障碍。 5.大量的单一实验室研究，包括： 语义记忆的专门化;韵律和信息的研究 孤独症与精神分裂症儿童的加工能力;发展 一项用于儿童的“思维障碍指数”;对遗传和 婴儿孤独症的免疫血液学因素和“惊吓”的研究 “反应”作为自闭症儿童脑干处理的一种测量方法。 目前正在开发的新项目之一是多实验室研究 儿童严重精神病理学的新分类系统。 这一项目将成为研究的一个特别重点 在更新期间。