INTERACTION OF T CELLS IN IMMUNITY & TOLERANCE

T 细胞在免疫中的相互作用

• 批准号: 3125338
• 负责人: JOHN W MOORHEAD
• 金额: $ 17.72万
• 依托单位: UNIVERSITY OF COLORADO DENVER
• 依托单位国家: 美国
• 财政年份: 1976
• 资助国家: 美国
• 起止时间: 1976-06-01 至 1991-06-30
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/3125338
• 关键词: T lymphocyte; affinity chromatography; antibody formation; antiidiotype antibody; cell cell interaction; cell population study; cellular immunity; clone cells; gel electrophoresis; haptens; hybridomas; immune response genes; immunofluorescence technique; immunoregulation; immunosuppression; leukocyte activation /transformation; lymphokines; major histocompatibility complex; monoclonal antibody; suppressor T lymphocyte; surface antigens

This project continues to investigate the cellular mechanisms which control thymus-dependent (T cell) immunity in contact hypersensitivity. Special emphasis is given to examining the properties of immune and suppressor T cells with respect to the nature of their antigen receptors and genetic interactions. We are continuing our studies on the antigen-specific suppressor factor with respect to its biological and physical/chemical properties.

这个项目继续研究控制细胞的机制 接触性超敏反应中的胸腺依赖(T细胞)免疫。特价 重点研究免疫T细胞和抑制T细胞的特性 关于它们的抗原受体的性质和遗传相互作用。 我们正在继续对抗原特异性抑制因子的研究 关于它的生物和物理/化学特性。