Engineered ion channels for selective and switchable ion conduction

用于选择性和可切换离子传导的工程离子通道

• 批准号: DP180100298
• 负责人: A/Prof Huacheng Zhang
• 金额: $ 29.6万
• 依托单位: RMIT University
• 依托单位国家: 澳大利亚
• 项目类别: Discovery Projects
• 财政年份: 2018
• 资助国家: 澳大利亚
• 起止时间: 2018-01-01 至 2021-12-31
• 项目状态: 已结题
• 来源: https://dataportal.arc.gov.au/RGS/Web/Grants/DP180100298
• 关键词: Engineered; ion; channels; selective; switchable

This project aims to develop an innovative bioinspired approach for fabricating angstrom-sized ion-channel membranes with specific ion selectivity, high ion conductivity and efficient gating function comparable to biological ion channels. Engineering of artificial channels with ion-channel-like shapes, ion selectivity filters and functional gates is expected to bring high-efficiency technologies to applications such as membrane separation and energy conversion. This project has potential to result in new knowledge of biomimetic design of artificial ion-channel membranes and directly benefit manufacturing industry for Australia.

本项目旨在开发一种创新的生物启发方法来制备具有特定离子选择性、高离子导电性和可与生物离子通道相媲美的高效门控功能的埃尺寸离子通道膜。具有离子通道形状的人工通道、离子选择性过滤器和功能门的工程有望将高效技术带到膜分离和能量转换等应用中。该项目有可能带来人造离子通道膜仿生设计的新知识，并直接惠及澳大利亚的制造业。