Chemo-prevention of tropical canine parasitoses and vector-borne diseases

热带犬寄生虫和媒介传播疾病的化学预防

• 批准号: LP170100187
• 负责人: Prof Rebecca Traub
• 金额: $ 17.31万
• 依托单位: The University of Melbourne
• 依托单位国家: 澳大利亚
• 项目类别: Linkage Projects
• 财政年份: 2018
• 资助国家: 澳大利亚
• 起止时间: 2018-03-15 至 2021-12-01
• 项目状态: 已结题
• 来源: https://dataportal.arc.gov.au/RGS/Web/Grants/LP170100187
• 关键词: Chemo; prevention; tropical; canine; parasitoses

This project will determine the prevalence and diversity of established, emerging and novel canine vector-borne agents and endoparasites in a tropical setting by using conventional and next generation molecular diagnostic tools. It will fill an important gap by providing independently-verified evidence on how well canine anti-parasitic products marketed in Australia and Asia by Bayer Animal Health, perform in high-infection pressure settings, as a chemo-preventative for these disease agents. Tropical regions spanning northern Australia and Southern Asia are highly conducive to a plethora of canine vector-borne and parasitic pathogens that cause significant morbidity and mortality in dogs. Many of these agents also pose a risk to public health. The outcomes will be directly translated to best-practice guidelines for the advancement of companion animal (and indirectly human) health and welfare.

该项目将通过使用传统和新一代分子诊断工具，确定热带环境中现有的、新兴的和新型的犬类媒介传播病原体和内寄生虫的流行率和多样性。它将填补一个重要的空白，通过提供独立验证的证据，证明拜耳动物健康公司在澳大利亚和亚洲销售的犬只抗寄生虫产品在高感染压力环境下作为这些疾病病原体的化学预防药物的表现如何。横跨澳大利亚北部和南亚的热带地区极易滋生大量犬类病媒传播的病原体和寄生性病原体，这些病原体会导致狗的严重发病率和死亡率。其中许多毒剂也对公众健康构成威胁。这些成果将直接转化为促进同伴动物(间接地为人类)健康和福利的最佳实践指南。