METHADONE MAINTENANCE DETOX OUTCOME--ROLE OF DETOX FEAR

美沙酮维持治疗完成的前景展望 戒毒和启动戒毒调整小于 50%的成果研究和完成率在19%之间。研究 这里提出的建议对以下方面具有直接影响和实际应用 提高戒毒效果。因为维修是第一位的 使用，调查人员发现，焦虑增加的前景 解毒。Cushman和Dole(1973)发现了他们样本的11% 康复后的维持性疾病患者流产戒毒 因为不断增加的焦虑。调查人员随后 确定戒毒恐惧的相关性并开发出可靠的 并对其采取有效措施，怀疑它是 维持戒毒效果差。但到目前为止，我们还没有 戒毒恐惧在戒毒中作用的直接证据 结果。 我们将跟踪随机抽样队列中的271名戒毒者 我们之前的研究和发现的大型维护计划 他们的美沙酮维持和戒毒结果。我们会 确定那些之前发现的戒毒者是否害怕 表现出完成戒毒的预期困难。我们会 通过现场详细的图表审查和个人工作实现这一点 采访了留在队列中的恐惧受试者。我们会 仔细评估恐惧对象，以确定他们是否没有 为他们的恐惧接受治疗，并单独分析数据 从那些有过的人那里。不管调查人员的假设是不是 在支持下，这项研究将提供科学上有用的美沙酮 大随机的维持和戒毒结果数据 来自3个地区、文化和地区的接受治疗的患者样本 种族不同的亚群。

Prospects for methadone maintenance patients completing detoxification and initiating a drug-free adjustment are less than 50% in outcome studies and completion rates range to 19%. Research proposed here has direct implications and practical application for improving detoxification outcome. Since maintenance was first used, investigators discovered increased anxiety at prospects of detoxification. Cushman and Dole (1973) found 11% of their sample of rehabilitated maintenance patients aborted detoxification because of increased anxiety. Investigators subsequently identified detoxification fear's correlates and developed reliable and valid measures for it, suspecting it as one of the culprits in poor maintenance detoxification outcome. But to date we have no direct evidence of detoxification fear's role in detoxification outcome. We will follow a random sample cohort of 271 treated addicts in 3 large maintenance programs from our previous research and discover their methadone maintenance and detoxification outcome. We will determine if those with previously identified detoxification fear show expected difficulty in completing detoxification. We will accomplish this through on site detailed chart reviews and personal interviews with fear subjects from the cohort who remain. We will carefully assess fear subjects to determine if they have not received treatment for their fear and analyze the data separately from those who have. Whether or not investigators' hypotheses are supported, the study will provide scientifically useful methadone maintenance and detoxification outcome data on a large random sample of treated patients from 3 geographically, culturally and racially different subpopulations.