THE DEVELOPMENT OF NEW SOFT LIMING MATERIALS

人们普遍认为没有真正令人满意的假牙 柔软的（有弹性的）衬里材料。 在艺术状态会议上， 1986年在华盛顿，J.W.斯坦福大学表示：“ 弹性衬垫的缺点主要在于缺乏持久性。 这一领域 似乎需要更多的研究支持”。 最近的研究 已经表明，失败的一个主要原因是这种材料的高吸水性 材料，因此我们的目标是生产弹性体聚合物， 有限的吸水量，因此寿命更长。 舒适度更高，成本更低 也是理想的性能。 因此，本研究的目的是：（1） 开发基于a）新型弹性体 甲基丙烯酸酯体系; B）有机硅/丙烯酸加合物体系，以实现低 吸水性2)分析和描述最成功的软 到目前为止的衬里材料，Molloplast B。3)仔细研究水 从纯水、水溶液和人工唾液中的吸附， 材料开发。 这将检验水的吸收是 由聚合物中的水溶性杂质控制。 而且 将有助于评估为什么原生质体B具有低吸水性。4)评价 在机械方面表现出低吸水性的材料， 粘弹性和微生物特性。5)评估的能力 固态核磁共振测量来表征牙科聚合物， 检测分子运动的显著差异， 化学结构以及单体和水含量。 假设， 可以测试的是，弛豫时间的变化提供了一个衡量 分子运动 三组基于有机硅产品的材料， 将研究粉末弹性体和固体商业弹性体。 这些 材料需要合成或特殊加工来制备。 的 配方不涉及在使用过程中滤出的增塑剂 性能 将根据选择获得成功的制剂 标准涉及三个筛选阶段。 合成与 初步筛选阈值将在伦敦医院进行 医学院，和表征和整个整合的计划 将在北卡罗来纳州大学完成。

It is generally recognized that there is no really satisfactory denture soft (resilient) lining material. At the state of art conference on restorative materials in Washington in 1986, J.W. Stanford stated "The resilient liners suffered principally from lack of permanence. This area appears to be one needing additional research support". Recent research has shown that a major cause of failure is the high water sorption of such materials and hence our objective is to produce elastomeric polymers with limited water uptake, and hence longer life. Greater comfort and less cost are also desirable properties. The aims of this study are therefore: 1) To develop new soft lining materials based on a) novel elastomeric methacrylate systems; b) silicone/acrylic adduct systems, to achieve low water sorption. 2) To analyze and characterize the most successful soft lining material to date, Molloplast B. 3) To study in detail the water sorption from pure water, aqueous solutions and artificial saliva, of the materials developed. This will test the hypothesis that water uptake is controlled by water soluble impurities in the polymer. Furthermore, it will help to evaluate why Molloplast B has low water uptake. 4) To evaluate the materials that exhibit low water uptake in terms of mechanical, visco-elastic and microbiological properties. 5) To evaluate the ability of solid-state NMR measurements to characterize dental polymers well enough to detect significant differences in molecular motion as a function of chemical structure as well as monomer and water content. The hypothesis to be tested is that changes in relaxation times provide a measure of molecular motion. Three groups of materials based on silicone products, powered elastomers and solid commercial elastomers will be studied. These materials require synthesis or special processing for preparation. The formulations do not involve plasticizers that leach out during service performance. Successful formulations will be obtained based on selection criteria which involve three stages of screening. Synthesis and preliminary selection thresholds will be carried out at London Hospital Medical College, and characterization and entire integration of the program will be accomplished at University of North Carolina.