Anti-Campylobacter Biofilm Technologies, to improve safety and shelf life of poultry products (AC-BIT)

该可行性项目将针对肉类供应链中微生物病原体形成的生物膜，以防止在人类食物链中传播。我们的模型将是弯曲杆菌和沙门氏菌的生物膜，这两种细菌是鸡肉皮肤/肉上食物中毒的重要原因，家禽包装材料中使用的塑料。将特别关注使用食品级酶和可食用天然产品（如辣根活性物质）可能抑制和去除这些生物膜。这项研究将建立在病原体生物膜、家禽生产、包装生产和天然产品化学方面的多学科专业知识基础上，这将为家禽包装或清洁产品行业的抗生素膜产品设计奠定基础，这些产品将在后续项目中用于MAP托盘、浸泡垫或家禽产品密封箔。这项工作将对英国的食物中毒产生影响，这对英国食品工业来说是一个重大挑战。据估计，每年约有100万例病例给英国经济造成的损失为15亿英镑，而被弯曲杆菌污染的家禽是英国食物中毒的主要单一原因，其经济负担估计为5.83亿英镑。

This feasibility project will target biofilms formed by microbial pathogens in the meat supply chain, to prevent transmission in the human food chain. Our model will be biofilms of Campylobacter and Salmonella, two bacteria which are important causes of food poisoning present on chicken skin/meat, with plastics used in poultry packaging materials. A particular focus will be given to the possible inhibition and removal of such biofilms using food-grade enzymes and edible natural products (such as horseradish actives). The research will build-up on multi-disciplinary expertise in pathogen biofilm, poultry production, packaging production and natural product chemistry This will underpin future research on the design of antibiofilm products for the poultry packaging or cleaning product industry, which will be used in subsequent project for usage in MAP trays, soaker pads or sealing foils with poultry products. This work will have an impact on food poisoning in the UK, which represents a major challenge to the UK food industry. The cost to the UK economy of the ~1 million cases is estimated at £1.5 bn per annum, and poultry contaminated with Campylobacter is a major single cause of food poisoning in the UK, with a financial burden estimated to be £583 million.