The role of LC3-associated phagocytosis during virus infection

LC3相关吞噬作用在病毒感染过程中的作用

• 批准号: BB/R009988/1
• 负责人: Tom Wileman
• 金额: $ 18.92万
• 依托单位: University of East Anglia
• 依托单位国家: 英国
• 项目类别: Research Grant
• 财政年份: 2018
• 资助国家: 英国
• 起止时间: 2018 至 无数据
• 项目状态: 已结题
• 来源: https://gtr.ukri.org/projects?ref=BB%2FR009988%2F1
• 关键词: role; LC3; associated; phagocytosis; during

Abstracts are not currently available in GtR for all funded research. This is normally because the abstract was not required at the time of proposal submission, but may be because it included sensitive information such as personal details.

目前GtR中并没有所有资助研究的摘要。这通常是因为在提交提案时不需要摘要，但也可能是因为摘要中包含个人详细信息等敏感信息。

项目成果

The ATG5-binding and coiled coil domains of ATG16L1 maintain autophagy and tissue homeostasis in mice independently of the WD domain required for LC3-associated phagocytosis.

• DOI: 10.1080/15548627.2018.1534507
• 发表时间: 2019-04
• 期刊: Autophagy
• 影响因子: 13.3
• 作者: Rai S;Arasteh M;Jefferson M;Pearson T;Wang Y;Zhang W;Bicsak B;Divekar D;Powell PP;Naumann R;Beraza N;Carding SR;Florey O;Mayer U;Wileman T
• 通讯作者: Wileman T

Control of infection by LC3-associated phagocytosis, CASM, and detection of raised vacuolar pH by the V-ATPase-ATG16L1 axis.

• DOI: 10.1126/sciadv.abn3298
• 发表时间: 2022-10-28
• 期刊: Science advances
• 影响因子: 13.6

Autophagy impairment by African swine fever virus.

• DOI: 10.1099/jgv.0.001637
• 发表时间: 2021-08
• 期刊: The Journal of general virology
• 作者: Shimmon GL;Hui JYK;Wileman TE;Netherton CL
• 通讯作者: Netherton CL

Regulation of cytokine signaling through direct interaction between cytokine receptors and the ATG16L1 WD40 domain.

通过细胞因子受体与ATG16L1 WD40结构域之间的直接相互作用来调节细胞因子信号传导。

• DOI: 10.1038/s41467-020-19670-4
• 发表时间: 2020-11-20
• 期刊: Nature communications
• 影响因子: 16.6
• 作者: Serramito-Gómez I;Boada-Romero E;Villamuera R;Fernández-Cabrera Á;Cedillo JL;Martín-Regalado Á;Carding S;Mayer U;Powell PP;Wileman T;García-Higuera I;Pimentel-Muiños FX
• 通讯作者: Pimentel-Muiños FX

Non-canonical autophagy functions of ATG16L1 in epithelial cells limit lethal infection by influenza A virus.

• DOI: 10.15252/embj.2020105543
• 发表时间: 2021-03-15
• 期刊: The EMBO journal
• 作者: Wang Y;Sharma P;Jefferson M;Zhang W;Bone B;Kipar A;Bitto D;Coombes JL;Pearson T;Man A;Zhekova A;Bao Y;Tripp RA;Carding SR;Yamauchi Y;Mayer U;Powell PP;Stewart JP;Wileman T
• 通讯作者: Wileman T