Biodegradable magnesium alloy scaffolds for bone tissue engineering

用于骨组织工程的可生物降解镁合金支架

• 批准号: DP170102557
• 负责人: Prof Cuie Wen
• 金额: $ 30.1万
• 依托单位: RMIT University
• 依托单位国家: 澳大利亚
• 项目类别: Discovery Projects
• 财政年份: 2017
• 资助国家: 澳大利亚
• 起止时间: 2017-04-21 至 2021-12-15
• 项目状态: 已结题
• 来源: https://dataportal.arc.gov.au/RGS/Web/Grants/DP170102557
• 关键词: Biodegradable; magnesium; alloy; scaffolds; bone

This project aims to develop a class of porous, biocompatible, biofunctional and biodegradable magnesium alloy scaffolds with designed pore architecture and mechanical properties mimicking those of natural bone for tissue engineering applications. These magnesium alloy scaffolds will be biocompatible, able to bear loads, and will be gradually replaced by natural bone. The outcomes are expected to benefit the ageing population and people with bone abnormalities.

本项目旨在开发一类多孔、生物相容性、生物功能和可生物降解的镁合金支架，其设计的孔隙结构和力学性能模仿天然骨，用于组织工程应用。这些镁合金支架将具有生物相容性，能够承受载荷，并将逐渐被天然骨所取代。研究结果有望使老龄人口和骨骼异常患者受益。