THERMAL IMAGING OF PERINATAL BEHAVIOR AND PHYSIOLOGY

围产期行为和生理学的热成像

• 批准号: 3329838
• 负责人: JEFFREY R ALBERTS
• 金额: $ 10.2万
• 依托单位: TRUSTEES OF INDIANA UNIVERSITY
• 依托单位国家: 美国
• 财政年份: 1991
• 资助国家: 美国
• 起止时间: 1991-06-01 至 1994-05-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/3329838
• 关键词: adrenalectomy; animal communication behavior; animal developmental psychology; brown fat; catecholamines; denervation; developmental neurobiology; embryo /fetus; imaging /visualization /scanning; laboratory rat; learning; newborn animals; noninvasive diagnosis; olfactory stimulus; oxygen consumption; perinatal; socializations; splanchnic nerves; sympathetic ganglion; thermogenesis; thermography; touch; triiodothyronine; ultrasound; vocalization

Recent findings from this laboratory suggest that infant rat pups' ultrasonic vocalization, oxygen utilization, respiration and non-shivering thermogenesis are functionally interrelated. We hypothesize that the pups' vocalizations are primarily the result of an adaptive, laryngeal/respiratory maneuver associated with phases of increased metabolic heat production and low oxygenation. To better understand the temporal and causal relationships among these correlated variables, we shall combine modern thermal imaging methods with other non-invasive techniques for measuring oxygen consumption, respiration and vocalization. Thermal imaging promises to provide real-time, highly accurate data on thermogenesis and patterns of body-warming and cooling that may explain changes in infant respiration and vocalization. A series of developmental and mechanistic analyses address the special problems, associated with the transition from fetal adaptations to infant adaptations. Thermal imaging will also be applied to postnatal behavior of infants during learning and in social settings, where traditional measurement techniques cannot be used due to mechanical interference. Together, these studies should provide new perspectives on perinatal behavior and physiology, particularly in relation to issues of respiration, thermal balance and communicatory signals.

该实验室的最新发现表明，幼鼠幼崽的 超声发声、氧气利用、呼吸和非颤抖 生热作用在功能上是相互关联的。我们假设这些幼崽的 发声主要是适应性的结果， 喉/呼吸动作与增高期相关 代谢产热和低氧合。为了更好地理解 这些相关变量之间的时间和因果关系，我们 应将现代热成像方法与其他非侵入性方法相结合 测量耗氧量、呼吸和发声的技术。 热成像有望提供实时、高度准确的数据 生热作用和体温和降温模式可以解释 婴儿呼吸和发声的变化。一系列发展中的 和机械分析解决了与 从胎儿适应过渡到婴儿适应。热成像 也将应用于婴儿在学习和学习期间的出生后行为 在社交环境中，传统的测量技术不能使用 由于机械干扰。总而言之，这些研究应该会提供新的 围产期行为和生理学的观点，特别是与 呼吸、热平衡和通讯信号的问题。