ENDOCRINE DETERMINANTS OF SEXUAL BEHAVIOR AND AROUSAL

这个应用程序试图澄清与荷尔蒙-行为相关的关系 在雌性恒河猴身上表现出社会性行为。一个 该提案的突出特点是包括远程测量 生殖道结构、心脏的信号躯体-内脏反应 四种不同接触方式对女性呼吸频率和心率的影响 性刺激的评估测试。使用生理学的 信息，生理性性唤醒的量化指标将是 建造的。该指数将被用来检查个体差异 在选定的女性中，关于表现出的前瞻和 接受行为。内分泌因素(雌二醇和睾酮)将是 监测和/或给药以确定它们对生理的影响 性唤醒、性唤醒与前向知觉的关系 可接受性。 该项目的目标有三个：1)促进 关于内分泌的APR(吸引力-前向性-接受性)理论 社会性行为的调解；2)与心理物理有关 性唤醒对外显行为的表现及其概念 处理能力和接受度；以及3)开始系统地 使用现有范围的性唤起功能障碍的问题 雌性恒河猴的个体差异。最终的临床益处 包括确定和治疗特定类型性行为 功能障碍，并进一步澄清性行为之间的关系 唤醒和支配/攻击性表现。

This application seeks to clarify hormone-behavior relationships associated with the display of sociosexual behavior in female rhesus monkeys. A prominent feature of the proposal is the inclusion of telemetrically signalled somatic-visceral responses of genital tract structures, heart rate, and respiration frequencies of females exposed to four differing assessment tests of sexual stimulation. Using the physiological information, a quantitative index of physiologic sexual arousal will be constructed. The index will be used to examine individual differences among selected females with regard to the display of proceptive and receptive behavior. Endocrine factors (estradiol and testosterone) will be monitored and/or administered to determine their effects on physiological sexual arousal, and on relationships between arousal and proceptivity and receptivity. Goals of the project are three-fold: 1) To contribute to refinement of "APR" (attractivity-proceptivity-receptivity) theory regarding endocrine mediation of sociosexual behavior; 2) To relate psychophysical manifestations of sexual arousal to overt behavior and the concepts of proceptivity and receptivity; and 3) To begin a systematic approach to problems of sexual arousal dysfunction by using existing ranges of individual differences among rhesus females. Ultimate clinical benefits include identification and treatment of specific types of sexual dysfunction, and futher clarification of relationships between sexual arousal and dominance/aggression manifestations.