NONSHARED ENVIRONMENT GENES & ADOLESCENT MENTAL HEALTH

描述(改编自申请人的摘要)：这是一项建议 收集以下子样本子样本的纵向跟踪(第二组)数据 有同性兄弟姐妹的家庭(719个原始家庭，450个随访 家庭)在1988-1990年期间进行了研究。最初的家庭由六个家庭组成 群体，(1)MZ双胞胎，(2)DZ双胞胎，(3)有完整兄弟姐妹的继母家庭， (4)有同父异母兄弟姐妹的继子女家庭；(5)有遗传背景的继子女家庭 无血缘关系的子女，(6)有完整兄弟姐妹的非离婚家庭。一位少校 最初项目的目标是评估共享环境的影响 以及对环境措施的加性和非加性遗传影响。 选择特定的族配置是为了最大限度地 设计的概念力量，而不是准确地估计 对美国有代表性的样本的影响程度。该样本， 然而，与其他发展中使用的那些相比，它是一个非常广泛的概念 学习。 在后续研究中，调查者计划评估7个领域的 环境、亲子互动(7项衡量标准，包括录像带 片段)，兄弟姐妹互动，(5个小节，包括一盘录像带 部门)、与非住宅父母的关系(1个仪器)、同行 人际关系(1个仪器)、同伴关系(1个仪器)、其他 (生活事件清单、社会支持)。还包括以下三个领域 结果指标；精神健康/疾病指标(5项指标，1项 录像片段)、个性发展强项(7项测量，1项 录像)和儿童青春期状况(1个测量标准)。一批 可能缓和非共享环境的家庭特征 还评估了影响；一般应激源(1个衡量标准)和军事 冲突(4项措施，1个录像片段)。此外，标准的社交媒体 并收集人口统计信息。数据将通过以下方式收集 由国家民意研究中心聘请和培训的采访者 (NORC)两次，相隔一周。纵向的目的是 组件是允许调查人员处理一系列复杂的 关于各种措施的变化力度的问题 提出(例如，遗传和环境对 随着时间的推移而改变？)

DESCRIPTION (Adapted from applicant's abstract): This is a proposal to collect longitudinal follow-up (second panel) data on a sub-sample of families with same-sex siblings (719 original families, 450 follow-up families) studied during 1988-1990. The original families consisted of six groups, (1) MZ twins, (2) DZ twins, (3) Step families with full siblings, (4) Step families with half siblings, (5) Step families with genetically unrelated children, (6) Non-divorced families with full siblings. A major goal of the initial project was to estimate shared environment influences and additive and non-additive genetic influences on environmental measures. The particular configuration of families was chosen to maximize the conceptual power of the design rather than precisely estimated the magnitude of effects on a representative sample of the U.S. The sample, however, is a very broad one relative to those used in other developmental studies. In the follow-up study the investigator plan to assess 7 domains of the environment, Parent-child interactions (7 measures, including a videotaped segment), sibling interaction, (5 measures, including a videotapes segment), relationships with non-residential parent(1 instrument), peer relationships (1 instrument), peer relationships (1 instrument), other (Life Event checklist, Social support). Also included are three domains of outcome measures; Mental health/Illness indicators (5 measures, 1 videotaped segment), Personality Developmental strengths (7 measures, 1 videotaped), and Child pubertal status (1 measure). A number of characteristics of the family that may moderate non-shared environmental effects are also assessed; General stressors (1 measure) and Martial conflict (4 measures, 1 videotaped segment). In addition, standard social and demographic information is gathered. The data will be collected by interviewers hired and trained by the National Opinion Research Center (NORC) on two occasion one week apart. The purpose of a longitudinal component is to allow the investigators to address a series of complex questions regarding the dynamics of change on the wide variety of measures proposed(e.g., does the relative influence of heredity and environment on change over time?)