MOTOR SYSTEMS COMPARATIVE STUDY
MOTOR SYSTEMS COMPARATIVE STUDY
批准号:
3410056
负责人:
STEVEN E BRAUTH
金额:
$5.07万
依托单位国家:
美国
项目类别:
财政年份:
1987
资助国家:
美国
项目状态:
已结题
起止时间:
1987-07-01 至 1990-06-30
关键词:
autoradiography basal ganglia biological models body movement efferent nerve fluorescent dye /probe histochemistry /cytochemistry immunochemistry jaw movement neural information processing neuroanatomy neurochemistry neuromuscular system neuropsychology neurotransmitters parasympathetic nervous system
中文摘要
本提案描述了一系列行为、解剖学
以及神经组织化学实验,旨在评估
爬行动物控制运动的神经系统,
凯门鳄。凯曼鳄鱼被选为动物
因为爬行动物的运动系统要简单得多
哺乳动物的生命。没有哺乳动物运动的直接等价物
皮质存在于爬行动物身上,但精确的运动和
尽管如此,协调仍然是行为的一部分
这些物种。试点工作表明,两个神经系统,都是
源自古纹状体,或基底节,参与
该物种对复杂运动的控制。第一个
它们来自苍白球,表达运动
主要通过视顶盖发挥作用。另一种派生自
腹侧苍白球内的神经元和投射到
传入运动神经元池的网状结构,如
三叉神经运动核。关于运动行为的一种新理论
爬行动物是高级的,它拥有苍白球散逸路径
控制方向和技术中介的行为,而
起源于腹侧苍白球的通路控制精度
运动,特别是下巴和嘴巴区域的运动。这些
这些系统在解剖和化学上是截然不同的。帕利多福格尔
神经元利用LANT6和GABA作为神经递质,而
苍白球腹侧区含有大量胆碱能神经元。
实验被用来检验假设,并进一步
评估化学、解剖学和行为学的相关性
两个系统都有。
英文摘要
The present proposal describes a series of behavioral, anatomical
and neurohistochemical experiments designed to evaluate the
neural systems underlying the control of movement in the reptile,
Caiman crocodilus. Caiman crocodilus was selected as an animal
model because the motor system of reptiles is simpler than that
of mammals. No direct equivalent of the mammalian motor
cortex is present in reptiles, yet precision movement and
coordination are nevertheless part of the behavioral repertoire of
these species. Pilot work indicates that two neural systems, both
derived from the paleostriatum, or basal ganglia, are involved in
the control of complex movement in this species. The first of
these is derived from the globus pallidus and expresses motor
functions largely via the optic tectum. The other is derived from
neurons in the ventral pallidum and projects upon portions of the
reticular formation afferent to motor neuron pools such as the
trigeminal motor nucleus. A new theory of motor behavior in
reptiles is advanced which holds that pallidofugal pathways
control orientation and tectally mediated behaviors, while the
pathways derived from the ventral pallidum control precision
movement, particularly of the jaws and mouth region. These
systems are anatomically and chemically distinct. Pallidofugal
neurons utilize LANT6 and GABA as neurotransmitters while the
ventral pallidal region contains many cholinergic neurons.
Experiments are proposed to test hypotheses and to further
evaluate the chemical, anatomical and behavioral correlates of
both systems.
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MOTOR SYSTEMS COMPARATIVE STUDY
-
批准号:3410059
-
项目类别:
-
资助金额:$4.33万
-
财政年份:1987
-
负责人:STEVEN E BRAUTH
-
依托单位:
MOTOR SYSTEMS COMPARATIVE STUDY
-
批准号:3410058
-
项目类别:
-
资助金额:$4.65万
-
财政年份:1987
-
负责人:STEVEN E BRAUTH
-
依托单位:
NEURAL BASIS OF ASSOCIATIVE LEARNING
-
批准号:2245025
-
项目类别:
-
资助金额:$14.26万
-
财政年份:1985
-
负责人:STEVEN E BRAUTH
-
依托单位:
NEURAL BASIS OF ASSOCIATIVE LEARNING
-
批准号:3486761
-
项目类别:
-
资助金额:$11.11万
-
财政年份:1985
-
负责人:STEVEN E BRAUTH
-
依托单位:
NEURAL BASIS OF ASSOCIATIVE LEARNING
-
批准号:3486762
-
项目类别:
-
资助金额:$13.18万
-
财政年份:1985
-
负责人:STEVEN E BRAUTH
-
依托单位:
NEURAL BASIS OF ASSOCIATIVE LEARNING
-
批准号:2245024
-
项目类别:
-
资助金额:$13.71万
-
财政年份:1985
-
负责人:STEVEN E BRAUTH
-
依托单位:
NEURAL BASIS OF ASSOCIATIVE LEARNING
-
批准号:3378982
-
项目类别:
-
资助金额:$5.27万
-
财政年份:1985
-
负责人:STEVEN E BRAUTH
-
依托单位:
NEURAL BASIS OF ASSOCIATIVE LEARNING
-
批准号:3378983
-
项目类别:
-
资助金额:$5.73万
-
财政年份:1985
-
负责人:STEVEN E BRAUTH
-
依托单位:
NEURAL BASIS OF ASSOCIATIVE LEARNING
-
批准号:3378981
-
项目类别:
-
资助金额:$5.96万
-
财政年份:1985
-
负责人:STEVEN E BRAUTH
-
依托单位:
NEURAL BASIS OF ASSOCIATIVE LEARNING
-
批准号:3486760
-
项目类别:
-
资助金额:$9.88万
-
财政年份:1985
-
负责人:STEVEN E BRAUTH
-
依托单位:
NEURAL BASIS OF ASSOCIATIVE LEARNING
-
批准号:3486759
-
项目类别:
-
资助金额:$9.23万
-
财政年份:1985
-
负责人:STEVEN E BRAUTH
-
依托单位:
NEURAL BASIS OF ASSOCIATION LEARNING
-
批准号:2245022
-
项目类别:
-
资助金额:$12.32万
-
财政年份:1985
-
负责人:STEVEN E BRAUTH
-
依托单位:
NEURAL BASIS OF ASSOCIATIVE LEARNING
-
批准号:3486758
-
项目类别:
-
资助金额:$8.46万
-
财政年份:1985
-
负责人:STEVEN E BRAUTH
-
依托单位:
海外基金