CYTOKINES, LIPID MEDIATOR IN REGULATORS OF CELL FUNCTION

细胞因子是由分泌或表面分泌的蛋白质介质。 在淋巴细胞和单核巨噬细胞上的表达 炎症或免疫抗原。所有的细胞因子都有一个共同的模式 通过与靶标表面的特定受体结合而发挥作用 细胞。某些细胞因子会导致第二种细胞因子的释放或 调节靶细胞功能的脂质介体。这个 细胞因子和脂质介质之间的相互作用可以是抑制的、相加的、 协同甚至导致产生前所未有的新奇效果 单独使用单个细胞因子或脂类介体。因此， 细胞因子的精确生物学作用将由 其他脂质介体的相互作用，以履行其在 细胞功能的调节。这将是有史以来第一次举行会议。 由FASE B夏季会议系列讨论细胞功能 细胞因子和脂质介质的相互作用 前列腺素、白三烯和PAF等针对强效 多种细胞因子的细胞功能：(白介素类、肿瘤坏死 因子和巨噬细胞集落刺激因子等)这是必要的 要透彻地了解这些方面的现有知识 各种因素及其与各种疾病发展的关系 病理生理状态。细胞因子及其作用机制的研究现状 细胞功能极高，目前对 科学界将举办这样的会议，让科学家 两个不同的活跃研究领域在一起讨论他们的想法， 最前沿的思想和交流信息 在安静和独特的环境中以开放的方式讨论生物医学话题。不是 这样的会议曾由FASB或任何其他协会在 相同或相似的主题。1984年，FASEB举办了一次夏季会议 《免疫药理学》，有一两个与此相似和相关的主题 会议。这次会议的独特之处将是出色的 计划和特邀演讲者在这两个研究领域。因此，这一点 会议作为其前身，将进一步刺激两个新的 并建立了调查人员对这一地区的新发现 努力吧。

Cytokines are protein mediators that are secreted from or surface expressed on lymphocyte-derived and mononuclear phagocytes in response to inflammation or immune antigens. All cytokines share a common mode of action by binding to specific receptors on the surface of the target cells. Certain cytokines will cause the release of second cytokines or lipid mediators that modulate the function of the target cells. The interaction of cytokines and lipid mediators can be inhibitory, additive, synergistic or even resulted in the generation of novel effects not seen with either individual cytokine or lipid mediator alone. Thus, the precise biological action of a cytokine will be determined by the interaction of other lipid mediators in order to fulfill its duty on the regulation of cell function. This will be the first conference ever held by the FASEB summer conference series dealing with the cellular function of the interaction of cytokines and lipid mediators such as prostaglandins, leukotrienes and PAF, etc. In view of the potent cellular function of various cytokines: (interleukins, tumor necrosis factor and macrophage colony stimulating factors, etc.) it is necessary to have a thorough understanding of the current knowledge of these factors and their relationship to the development of various pathophysiological states. The current interest on cytokines and their cellular functions is extremely high and is of current interest to the scientific community to have this kind of conference to bring scientists of two different active research areas together to discuss their ideas, thoughts and exchange information on the cutting edge of the most current biomedical topics in an open manner at a quiet and unique setting. No such conference was ever held by FASEB or any other association on the same or similar topic. In 1984, FASEB held a summer conference on "Immmopharmacology" with one or two topics similar and related to this conference. The unique feature of this conference will be the excellent program and invited speakers in these two areas of research. Thus, this conference as its predecessors, will serve to further stimulate both new and established investigators to new discoveries in this area of endeavor.