GENETIC ANALYSIS WORKSHOP IV: PRE-WORKSHOP MEETING

自1982年以来，遗传分析研讨会（GAW）每年在 美国人类遗传学会的会议 施行本 讲习班的目的是提供一种评价和比较 人类谱系和人群的不同统计分析方法 数据 遗传分析研讨会IV（GAW IV）将于1985年10月9日举行 在湖城的ASHG会议上。 与前三个相比， 第四次全球大气观察将专门讨论几组真实的数据（而不是 计算机模拟数据），选自其中具有 对先前分析的解释存在争议。 受试者 区域包括（1）11号染色体标记;（2）乳腺癌;（3） 亨廷顿氏病;和（4）HLA相关疾病（胰岛素依赖性 糖尿病、乳糜泻和多发性硬化症）。 在GAW之前 第四，计划举行为期两天的会议，研讨会与会者将 讨论其分析结果，并编写综合摘要， 在GAW IV上的演示。 会议还将包括以下人员的发言： 参与每例受试者数据收集的个人 区域，以及方法论问题，理论问题的讨论 等与每个领域相关。 本次资助申请旨在寻求 为本次研讨会提供资金。

The Genetic Analysis Workshops (GAW) have been held each year since 1982 at the American Society of Human Genetics meetings. The purpose of these workshops has been to provide a mechanism for evaluation and comparison of different methods of statistical analysis of human pedigree and population data. Genetic Analysis Workshop IV (GAW IV) will be held October 9, 1985 at the ASHG meetings in Salt Lake City. In contrast to the first three workshops, GAW IV will be devoted to several sets of real data (rather than computer-simulated data), selected from subject areas in which there has been controversy over the interpretation of previous analyses. The subject areas include (1) chromosome 11 markers; (2) breast cancer; (3) Huntington's disease; and (4) HLA-related diseases (insulin dependent diabetes mellitus, coeliac disease and multiple sclerosis). Prior to GAW IV, a two day meeting is being planned at which workshop participants will discuss results of their analyses and prepare integrated summaries for presentation at GAW IV. The meeting also will include presentations by individuals who have been involved in data collection for each subject area, as well as discussions of methodological issues, theoretical problems etc. relevant to each area. The aim of this grant application is to seek funding for this pre-workshop meeting.