OXIDATIVE DAMAGE AND REPAIR

国际自由基协会第五届两年一度的会议 研究（SFRR国际）将题为“氧化损伤和 修复”，并将于1990年11月14日至20日在帕萨迪纳举行， 加州。会议对协会成员和非成员开放， 在平等的基础上，并旨在吸引基础科学家， 临床科学家、毒理学家和临床医生。目前的估计 （根据国际森林论坛两年期会议的结果， 资料）表明，在2000年可能有800至1 000名与会者登记， 了那次会议 这一领域以前的会议都集中在基础科学上， 自由基生物学的一些方面。虽然这个问题将被涵盖，我们 计划突出两个新的领域，目前非常感兴趣：1） 参与“氧化应激”基因和蛋白质的修复， 氧化损伤，2）在各种疾病中使用抗氧化疗法 疾病状态、急性损伤和慢性损伤（如长期 烟雾）。修复氧化损伤的DNA、蛋白质和 脂质是一个新的研究领域， 氧化应激许多参与这种修复的酶系统 似乎是可诱导的氧化应激蛋白，会议将 提供了第一个直接比较氧化应激和热的论坛 休克基因和蛋白质。缺血/再灌注的抗氧化治疗 损伤（心脏病发作，中风等），癌症（包括光动力学 治疗），类风湿性关节炎，动脉粥样硬化，烧伤/创伤，炎症， 各种各样的眼疾正在被设计出来，或者已经被设计出来了。 正在进行临床试验“氧化损伤与修复”将以 自由基医学的这些重要方面的每一个会议。 SFRR国际由四个成员协会组成：SFRR欧洲， SFRR日本，SFRR澳大拉西亚，和氧气协会（'SFRR美国'）。的 两年一次的SFRR国际会议是主要的国际会议 在这个蓬勃发展的跨学科领域。以往的两年期会议 在伦敦（1982年）、约克（1984年）、杜塞尔多夫（1986年）和京都举行过 （1988年），注册人数逐渐增加（ 京都）。我的领域还支持两个成功的期刊：“自由基” 生物学与医学”和“自由基研究通讯”。我们希望 吸引大量非会员参加“氧化损伤与修复”， 特别是心脏病学家、肿瘤学家、风湿病学家， 眼科医生，除了生物化学家，药理学家， 毒理学家和分子生物学家。 “氧化损伤与修复”的科学计划进行了辩论， 根据提案，由当地组织委员会（12名成员）批准 国际咨询委员会成员（18个成员国中的41个成员） 国家）。为了确保最大限度的参与和介绍 最新的研究和临床发现，会议将只邀请一些 占发言人总数的40%。大约60%的演讲者将 由会议主席从提交的摘要中选出。其余 摘要将在海报会议期间发表。一本抽象的 “自由基生物学与医学”，以及一本会议记录书将在 公开.

The 5th Biennial Meeting of the International Society for Free Radical Research (SFRR International) will be entitled '"Oxidative Damage & Repair", and will be held from November 14-20, 1990 in Pasadena, California. The meeting is open to society members and non-members alike, on an equal basis, and has been designed to attract basic scientists, clinical scientists, toxicologists, and clinicians. Current estimates (based on past Biennial Meetings of SFRR International, and requests for information) indicate a potential registration of 800 to 1,000 conferees at the meeting. Previous meetings in this field have concentrated on the basic science aspects of free radical biology. Although this subject will be covered, we plan to highlight two newer areas of great current interest: 1) The involvement of "oxidative stress' genes and proteins in the repair of oxidative damage, and 2) The use of antioxidant therapies in various disease states, acute injuries, and chronic injuries (such as prolonged exposure to smog). The repair of oxidatively damaged DNA, proteins, and lipids is a new area of inquiry on the cutting edge of research into oxidative stress. Many of the enzymatic systems involved in such repair appear to be inducible oxidative stress proteins, and the meeting will provide the first forum for direct comparisons of oxidative stress and heat shock genes and proteins. Antioxidant therapies for ischemia/reperfusion injuries (heart attacks, strokes, etc), cancer (including photodynamic therapy), rheumatoid arthritis, atherosclerosis, burn/trauma, inflammation, and various diseases of the eye are being devised, or are already undergoing clinical trials. 'Oxidative Damage & Repair' will feature sessions on each of these important aspects of free radical medicine. SFRR International is comprised of four constituent societies: SFRR Europe, SFRR Japan, SFRR Australasia, and The Oxygen Society ('SFRR America'). The Biennial Meeting of SFRR International is the major international meeting in this blossoming interdisciplinary field. Previous Biennial Meetings have been held in London (1982), York (1984), Dusseldorf (1986), and Kyoto (1988), with progressively increasing registrations (950 conferees in Kyoto). 'Me field also supports two successful journals: "Free Radical Biology & Medicine', and 'Free Radical Research Communications'. We hope to attract large numbers of non-members to 'Oxidative Damage & Repair", particularly cardiologists, oncologists, rheumatologists, and ophthalmologists, in addition to biochemists, pharmacologists, toxicologists, and molecular biologists. The scientific program for "Oxidative Damage & Repair" was debated and approved by the Local Organizing Committee (12 members), based on proposals made by members of the International Advisory Board (41 members from 18 countries). To ensure maximal participation and the presentation of the latest research and clinical findings, the meeting will only invite some 40% of the total number of speakers. Approximately 60% of the speakers will be selected, by session chairs, from the submitted abstracts. The remaining abstracts will be presented during poster sessions. An abstract volume of 'Free Radical Biology & Medicine', and a proceedings book will be published.