SYMPOSIUM AND STATE OF THE ART LECTURES

请求提供资金，以支持一个名为“类固醇”的研讨会 生殖中的荷尔蒙受体“和三个最先进的讲座 将在第24届中国环境科学研究会年会上发表 繁殖。会议将于1991年7月27日至29日在 不列颠哥伦比亚大学，温哥华，卑诗省 选择演讲是因为他们及时的兴趣和他们的 强调使用分子和细胞方法适用于 生殖生物学的广泛研究。研讨会将是 致力于类固醇激素受体在生殖中的作用 功能。被邀请的演讲者来自国内和国际。 该领域公认的专家。伯特·奥马利博士将给一个 类固醇受体作用的分子机制研究进展 超级大家庭。让·威尔逊博士将讨论分子缺陷 导致基因异常的雄激素受体 男性。埃德温·米尔格罗姆博士将阐述分子和细胞 孕激素和抗孕激素的作用机制 黄体酮受体。 最先进的讲座旨在代表当前和 在生殖生物学方面的令人兴奋的探索，并对 与会者范围很广。保罗·瓦萨曼博士将讨论细胞和 哺乳动物受精的分子机制。泽纳·沃布博士 将讨论她在生长因子的作用方面的激动人心的工作 胚胎着床前发育的逆行方法 转录与聚合酶链式反应相结合。菲利斯博士 Wise将讨论她最近开发的方法，使用 反向溶血空斑原位杂交法监测 同时，脑下垂体激素分泌和基因表达 单个细胞。 研讨会的会议记录和最先进的讲座将 发表在《生殖生物学》上。

Funds are requested to help support a Symposium entitled "Steroid Hormone Receptors in Reproduction" and three State-of-the-Art Lectures to be presented at the 24th Annual meeting of the Society for the Study of Reproduction. The meeting will be held July 27-29, 1991 at the University of British Columbia, Vancouver, B.C. The presentations were selected for their timely interest and their emphasis on the use of molecular and cellular approaches applicable to a wide range of studies in Reproductive Biology. The symposium will be devoted to the role of steroid hormone receptors in reproductive functions. The invited speakers are nationally and internationally recognized experts in this field. Dr. Bert O'Malley will give an overview of the molecular mechanisms of action of the steroid receptor superfamily. Dr. Jean Wilson will discuss molecular defects in the androgen receptor that cause a spectrum of abnormalities in genetic males. Dr. Edwin Milgrom will address the molecular and cellular mechanism of action of progestins and antiprogestins as mediated through the progesterone receptor. The State-of-the-Art Lectures are designed to represent current and exciting exploration in Reproductive Biology and to be of interest to a wide range of attendees. Dr. Paul Wassarman will discuss the cell and molecular mechanisms involved in mammalian fertilization. Dr. Zena Werb will discuss her exciting work on the function of growth factors during embryonic preimplantation development using the methods of reverse transcription coupled with the polymerase chain reaction. Dr. Phyllis Wise will discuss the methods she has recently developed using a combined reverse hemolytic plaque assay with in situ hybridization to monitor, simultaneously, pituitary hormone secretion and gene expression within individual cells. Proceedings of the Symposium and State-of-the-Art Lectures will be published in Biology of Reproduction.