SYMPOSIUM AND STATE OF THE ART LECTURES

要求提供资金，以帮助支持题为“类固醇”的专题讨论会 生殖中的激素受体”和三个最先进的讲座， 将在第24届年会上提出的社会研究 生殖。 会议将于1991年7月27日至29日在 不列颠哥伦比亚省大学，不列颠哥伦比亚省温哥华 选择这些专题介绍是因为它们及时引起人们的兴趣， 强调使用分子和细胞的方法适用于 广泛的生殖生物学研究。 研讨会将在 研究类固醇激素受体在生殖系统中的作用 功能协调发展的 受邀演讲者来自国内和国际 这一领域公认的专家。 伯特·奥马利博士将在 类固醇受体作用的分子机制概述 超家族 吉恩·威尔逊博士将讨论 雄激素受体导致一系列遗传异常， 男性。 埃德温·米尔格罗姆博士将在分子和细胞 孕激素和抗孕激素的作用机制， 孕酮受体 最先进的讲座旨在代表当前和 令人兴奋的探索生殖生物学和感兴趣的一个 广泛的参与者。 Paul Wassarman博士将讨论细胞， 哺乳动物受精的分子机制。 Zena Werb博士 将讨论她的令人兴奋的工作对生长因子的功能， 胚胎植入前发育的方法， 转录与聚合酶链反应偶联。 菲利斯医生 怀斯将讨论她最近开发的方法， 用原位杂交进行反向溶血空斑测定以监测， 同时，垂体激素分泌和基因表达， 单个细胞。 研讨会和最新技术讲座的会议记录将在 发表在《生殖生物学》上。

Funds are requested to help support a Symposium entitled "Steroid Hormone Receptors in Reproduction" and three State-of-the-Art Lectures to be presented at the 24th Annual meeting of the Society for the Study of Reproduction. The meeting will be held July 27-29, 1991 at the University of British Columbia, Vancouver, B.C. The presentations were selected for their timely interest and their emphasis on the use of molecular and cellular approaches applicable to a wide range of studies in Reproductive Biology. The symposium will be devoted to the role of steroid hormone receptors in reproductive functions. The invited speakers are nationally and internationally recognized experts in this field. Dr. Bert O'Malley will give an overview of the molecular mechanisms of action of the steroid receptor superfamily. Dr. Jean Wilson will discuss molecular defects in the androgen receptor that cause a spectrum of abnormalities in genetic males. Dr. Edwin Milgrom will address the molecular and cellular mechanism of action of progestins and antiprogestins as mediated through the progesterone receptor. The State-of-the-Art Lectures are designed to represent current and exciting exploration in Reproductive Biology and to be of interest to a wide range of attendees. Dr. Paul Wassarman will discuss the cell and molecular mechanisms involved in mammalian fertilization. Dr. Zena Werb will discuss her exciting work on the function of growth factors during embryonic preimplantation development using the methods of reverse transcription coupled with the polymerase chain reaction. Dr. Phyllis Wise will discuss the methods she has recently developed using a combined reverse hemolytic plaque assay with in situ hybridization to monitor, simultaneously, pituitary hormone secretion and gene expression within individual cells. Proceedings of the Symposium and State-of-the-Art Lectures will be published in Biology of Reproduction.