ANIMAL RESOURCE IMPROVEMENT GRANT

动物护理部设有一个中心实验室 俄勒冈州健康科学大学校园的动物设施 以及俄勒冈州希尔斯伯勒附近一个178英亩的农场。 动物护理 设施获得AAALAC认证;然而，25年 旧校园设施需要不断翻新，新设备 和新笼，以充分维持AAALAC标准， 动物护理 18,000平方米ft校园设施分为两个独立的 路段 二楼是啮齿动物和兔子的家。 第一 地板上住着大型动物，如羊、狗、猪和猴子。 一楼的活动中心围绕着 实验手术室，动物准备室， 重症监护室和器械准备室。 最 涉及动物的手术和所有生存手术 在OHSU的计划和监测在这方面。 本提案中要求的翻修是必要的， 一个有25年历史的设施，不是为了服务于 1986年所需的复杂实验程序。 胎儿 手术，肝移植，心脏移植，胰腺 移植，血脑屏障破坏程序，额外 心脏血氧合手术，血管内激光 外科手术、心室辅助泵程序和心肺 当这个动物护理机构 建于1961年。 我们预计OHSU的外科医生将执行 超过200例绵羊胎儿手术，50例狗肝移植手术， 猪，16例猴子心肺移植，许多研讨会 以及肾脏移植和严重创伤的培训课程 和救生程序

The Department of Animal Care operates a central laboratory animal facility at the Oregon Health Sciences University campus and a 178 acre farm near Hillsboro, Oregon. The animal care facilities are AAALAC accredited; however, the twenty-five year old campus facility requires continual renovation, new equipment and new cages to adequately maintain the AAALAC standards of animal care. The 18,000 sq. ft campus facility is divided into two separate sections. The second floor houses rodents and rabbits. The first floor houses large animals such as sheep, dogs, pigs, and monkeys. The center of activity on the first floor revolves around the experimental surgery suites, the animal preparation room, the intensive care room, and the instrument preparation room. Most procedures involving animals and all survival surgeries conducted at OHSU are scheduled and monitored in this area. The renovations requested in this proposal are necessary to update a 25 year old facility which was not designed to service the sophisticated experimental procedures required in 1986. Fetal surgery, liver transplants, heart transplants, pancreatic transplants, blood brain barrier disruption procedures, extra corporeal blood oxygenation procedures, intravascular laser surgery, ventricular assist pump procedures, and heart lung transplants were not common when this animal care facility was constructed in 1961. We project that OHSU surgeons will perform over 200 fetal surgeries in sheep, 50 liver transplants in dogs and pigs, sixteen heart lung transplants in monkeys, many workshops and training classes in kidney transplants and advanced trauma and lifesaving procedures.