A NEW FINGER JOINT PROSTHESIS

设计并测试了一种新型的指关节假体。 它将 使用钛铰链。 铰链区域将被封装在 其外部具有整体纹理表面的弹性护套 旨在促进软组织向内生长和附着。 这潜在地 最大限度地减少反应性疤痕组织形成周围的弯曲部分的 植入物，从而改善关节功能。 锥形近端和 假体的远端终端将利用多孔的烧结金属 允许在不使用粘合剂的情况下植入器械的表面 当插入骨的骨髓腔时，骨水泥。 骨生长 进入多孔金属表面是固定的手段。 一个完全多孔的 表面装置还提供了降低细菌感染的可能性的优点， 植入部位的定植，通常是一种灾难性的并发症， 矫形假肢 一系列的12个原型将进行弯曲测试， 体外1000万次循环，以表征器械可靠性。 以下 即，6个假体然后将被植入成人新的膝关节中。 新西兰白色家兔，带硅橡胶关节垫片假体 对侧植入作为对照。 8周后，动物将 牺牲，假体和周围组织被移除， 使用光学和扫描电子显微镜进行组织病理学评价。 一 器械固定和组织囊结构的定量比较 将成为可能。

A new finger joint prosthesis is to be designed and tested. It will utilize a titanium hinge. The hinge area is to be encapsulated in an elastomeric jacket whose exterior will have an integrally textured surface designed to promote soft tissue ingrowth and attachment. This potentially minimizes reactive scar tissue formation around the flexing part of the implant, resulting in improved joint function. The tapered proximal and distal terminations of the prosthesis will utilize a porous, sintered metal surface to permit implantation of the device without the use of adhesive cements when inserted into the medullary cavity of the bone. Bone growth into the porous metal surface is the means of fixation. A totally porous surface device offers the advantage also of reduced potential for bacterial colonization of the implant site, a generally disastrous complication with orthopedic prostheses. A series of 12 prototypes will be flex tested in vitro for 10 million cycles to characterize device reliability. Following that, 6 prostheses will then be implanted in the knee joint of adult New Zealand white rabbits, with silicone rubber joint spacer prostheses contralaterally implanted as controls. After 8 weeks, the animals will be sacrificed, and the prostheses and surrounding tissues removed for histopathologic evaluation using light and scanning electron microscopy. A quantitative comparison of device fixation and tissue capsule structure will then be possible.