CROSS-AXIS COIL PLANET CENTRIFUGE CHROMATOGRAPH

十字轴线圈行星离心机色谱仪

• 批准号: 3498155
• 负责人: MARTHA KNIGHT
• 金额: $ 5万
• 依托单位: PEPTIDE TECHNOLOGIES CORPORATION
• 依托单位国家: 美国
• 财政年份: 1988
• 资助国家: 美国
• 起止时间: 1988-08-01 至 1989-01-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/3498155
• 关键词: aminoacid analyzer; biomedical automation; biomedical equipment development; centrifugation; fluid; fluid flow; health economics; high performance liquid chromatography; liquid chromatography; peptide chemical synthesis; solvents; synthetic peptide; thin layer chromatography

A new countercurrent chromatography instrument, the cross-axis flow-through coil planet centrifuge is proposed for the preparative chromatography of peptides. This is an apparatus that separates substances according to their partitioning in a liquid-liquid equilibration system without the use of a solid-phase support. The instrument will be tested in the purification of large quantities of synthetic peptides, using different conditions and solvent systems to achieve high resolution and recovery. The successful development of this instrument would make available a lower cost technology for chromatographic purification.

一种新型逆流色谱仪--十字轴 提出了一种直通式螺旋管行星离心机， 肽的制备色谱法。 这是一种仪器 它根据物质在一个 不使用固相的液-液平衡系统 支持. 该仪器将在大型纯化中进行测试 大量的合成肽，使用不同的条件和 溶剂系统可实现高分辨率和回收率。 的 这一工具的成功开发将提供一个 色谱纯化的低成本技术。