课题基金 / 基金详情

CROSS-AXIS COIL PLANET CENTRIFUGE CHROMATOGRAPH

CROSS-AXIS COIL PLANET CENTRIFUGE CHROMATOGRAPH
十字轴线圈行星离心机色谱仪
批准号：
3498155
负责人：
MARTHA KNIGHT
金额：
$5.0万
依托单位：
PEPTIDE TECHNOLOGIES CORPORATION
依托单位国家：
美国
项目类别：
财政年份：
1988
资助国家：
美国
项目状态：
已结题
起止时间：
1988-08-01 至 1989-01-31
来源：
https://reporter.nih.gov/project-details/3498155
关键词：
aminoacid analyzer biomedical automation biomedical equipment development centrifugation fluid fluid flow health economics high performance liquid chromatography liquid chromatography peptide chemical synthesis solvents synthetic peptide thin layer chromatography

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中文摘要
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英文摘要
A new countercurrent chromatography instrument, the cross-axis flow-through coil planet centrifuge is proposed for the preparative chromatography of peptides. This is an apparatus that separates substances according to their partitioning in a liquid-liquid equilibration system without the use of a solid-phase support. The instrument will be tested in the purification of large quantities of synthetic peptides, using different conditions and solvent systems to achieve high resolution and recovery. The successful development of this instrument would make available a lower cost technology for chromatographic purification.
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