PEDIATRIC INTRA-AORTIC BALLOON PUMP

静脉空气栓塞，这可能发生在各种临床 在某些情况下，特别是坐着的神经外科病例， 如果空气到达全身， 循环（心脏和大脑）。 第一阶段的研究已经证明 （1）早期发现和排除空气（<45秒）; 2)导管 配置（阻力、长度和位置）;以及3）抽吸 流速（最小250 cc/min）都是至关重要的 成功清除了空气栓塞。 在第二阶段，我们将制造和测试一个完整的临床 包括远程致动真空的静脉空气回收系统 储液器和泵、压力监测器、导管（用于回收 心脏上方和下方的空气入口）、管路套件和空气检测 方法. 安全可靠的自动静脉空气回收系统 通过早期有效的血管空气检测， 护理有空气栓塞风险的患者， 发病率和死亡率。

Venous air embolism, which may occur in a variety of clinical circumstances, particularly sitting neurosurgical cases, can be lethal or cause severe morbidity if the air reaches the systemic circulation (heart and brain). Phase I studies have demonstrated that: 1) early air detection and removal (<45 sec.); 2) catheter configuration (resistance, length, and position); and 3) aspiration flow rate (minimum of 250 cc/min.) are all critical to the successful removal of bolus air emboli. During Phase II we will fabricate and test a complete clinical venous air retrieval system including a remotely actuated vacuum reservoir and pump, pressure monitors, catheters (for retrieval of air entry above and below the heart), tubing set, and air detection methods. A safe, reliable automated venous air retrieval system with early, effective vascular air detection could standardize the care of patients at risk for air embolism and decrease the morbidity and mortality.