PEDIATRIC INTRA-AORTIC BALLOON PUMP

儿科主动脉内球囊泵

• 批准号: 3508492
• 负责人: JEFFREY L ORTH
• 金额: $ 20.63万
• 依托单位: ROCKY MOUNTAIN RESEARCH, INC.
• 依托单位国家: 美国
• 财政年份: 1988
• 资助国家: 美国
• 起止时间: 1988-04-07 至 1990-04-06
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/3508492
• 关键词: air embolism; antithrombogenic surface; biomaterial interface interaction; biomedical equipment safety; biosensor device; clinical biomedical equipment; diagnostic catheterization; dogs; early diagnosis; patient monitoring device; phantom model; ultrasound blood flow measurement

Venous air embolism, which may occur in a variety of clinical circumstances, particularly sitting neurosurgical cases, can be lethal or cause severe morbidity if the air reaches the systemic circulation (heart and brain). Phase I studies have demonstrated that: 1) early air detection and removal (<45 sec.); 2) catheter configuration (resistance, length, and position); and 3) aspiration flow rate (minimum of 250 cc/min.) are all critical to the successful removal of bolus air emboli. During Phase II we will fabricate and test a complete clinical venous air retrieval system including a remotely actuated vacuum reservoir and pump, pressure monitors, catheters (for retrieval of air entry above and below the heart), tubing set, and air detection methods. A safe, reliable automated venous air retrieval system with early, effective vascular air detection could standardize the care of patients at risk for air embolism and decrease the morbidity and mortality.

静脉空气栓塞症，可发生在多种临床 情况，特别是坐着的神经外科病例，可能是 如果空气到达全身的话会致命或导致严重的疾病 循环(心脏和大脑)。第一阶段的研究表明 即：1)早期空气检测和排出(&lt；45秒)；2)导管 构型(阻力、长度和位置)；3)吸气 流速(最小250毫升/分钟)都是至关重要的 气栓成功取出术。 在第二阶段，我们将制造和测试一个完整的临床 包括遥控真空的静脉空气回收系统 储液器和泵、压力监测器、导管(用于回收 心脏上方和下方的进气口)、管件和空气检测 方法：研究方法。一种安全可靠的静脉空气自动回收系统 早期、有效的血管空气检测可以标准化 护理空气栓塞症高危患者，减少 发病率和死亡率。