Clonal haematopoiesis of indeterminate potential (CHIP) and its consequences for blood cancers, cardiovascular disease and stroke – the ASPREE-CHIP sub-study
Clonal haematopoiesis of indeterminate potential (CHIP) and its consequences for blood cancers, cardiovascular disease and stroke – the ASPREE-CHIP sub-study
不确定潜能克隆造血 (CHIP) 及其对血癌、心血管疾病和中风的影响 — ASPREE-CHIP 子研究
批准号：
nhmrc : GNT1163002
负责人：
金额：
$141.66万
依托单位：
依托单位国家：
澳大利亚
项目类别：
Project Grants
财政年份：
2019
资助国家：
澳大利亚
项目状态：
已结题
起止时间：
2019-01-01 至 --
中文摘要
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英文摘要
Acquired genetic mutations normally associated with blood cancers like leukaemia can be detected in the blood or bone marrow long before any disease appears. Known as CHIP (clonal haematopoiesis of indeterminate potential), it is more common in older age, and has been associated with other health problems common in the elderly, like heart disease and stroke. We will study how common CHIP is, and its health consequences, in a large clinical trial of otherwise healthy people aged 70 or older.
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