Cluster randomised trial comparing one versus two doses of ivermectin for mass drug administration to control scabies

比较一剂与两剂伊维菌素大规模给药控制疥疮的整群随机试验

• 批准号: nhmrc : 1127297
• 负责人: Dr Lucia Romani
• 金额: $ 36.88万
• 依托单位: Murdoch Childrens Research Institute
• 依托单位国家: 澳大利亚
• 项目类别: Project Grants
• 财政年份: 2017
• 资助国家: 澳大利亚
• 起止时间: 2017-01-01 至 2019-12-31
• 项目状态: 已结题
• 来源: https://researchdata.edu.au/cluster-randomised-trial-control-scabies/947986
• 关键词: Cluster; randomised; trial; comparing; versus

Scabies is a common skin disease in developing countries, in particular in the Pacific region. In the Western Province of Solomon Islands, one in two children suffer from the infestation, and 20% of the population. We know that mass drug administration with two doses of oral ivermectin is effective to reduce the burden of scabies in the community. We now propose a study to determine whether one single dose is as effective. This would have major public health benefits.

疥疮是发展中国家，特别是太平洋地区的常见皮肤病。在所罗门群岛西部省，二分之一的儿童以及 20% 的人口遭受感染。我们知道，大规模给药两剂口服伊维菌素可有效减轻社区疥疮负担。我们现在提出一项研究来确定单剂量是否同样有效。这将带来重大的公共健康益处。