Cluster randomised trial comparing one versus two doses of ivermectin for mass drug administration to control scabies

疥疮是发展中国家，特别是太平洋区域的一种常见皮肤病。在所罗门群岛的西部省，每两个儿童中就有一个受到这种侵扰，占人口的20%。我们知道，大规模药物管理与两个剂量的口服伊维菌素是有效的，以减少疥疮在社区的负担。我们现在提出一项研究，以确定是否一个单一的剂量是有效的。这将带来重大的公共卫生效益。

Scabies is a common skin disease in developing countries, in particular in the Pacific region. In the Western Province of Solomon Islands, one in two children suffer from the infestation, and 20% of the population. We know that mass drug administration with two doses of oral ivermectin is effective to reduce the burden of scabies in the community. We now propose a study to determine whether one single dose is as effective. This would have major public health benefits.