CONTROL OF GRANULOSA CELL PROLIFERATION/DIFFERENTIATION

颗粒细胞增殖/分化的控制

• 批准号: 2200519
• 负责人: JOHN J PELUSO
• 金额: $ 10万
• 依托单位: UNIVERSITY OF CONNECTICUT SCH OF MED/DNT
• 依托单位国家: 美国
• 财政年份: 1992
• 资助国家: 美国
• 起止时间: 1992-09-30 至 1995-09-29
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/2200519
• 关键词: antisense nucleic acid; aromatase; cell differentiation; cell growth regulation; cyclic AMP; estrogens; gel mobility shift assay; gene expression; genetic transcription; granulosa cell; growth factor; hormone regulation /control mechanism; laboratory rat; phorbols; protooncogene; tissue /cell culture; transcription factor; transfection

This is a Shannon Award providing partial support for research projects that fall short of the assigned institute's funding range but are in the margin of excellence. The Shannon award is intended to provide support to test the feasibility of the approach; develop further tests and refine research techniques; perform secondary analysis of available data sets; or conduct discrete projects that can demonstrate the PI's research capabilities or lend additional weight to an already meritorious application. Further scientific data for the CRISP System are unavailable at this time.

这是一个香农奖，为研究项目提供部分支持 不属于指定研究所的资助范围，但在 卓越的边缘。 香农奖旨在提供支持 测试该方法的可行性;开发进一步的测试和改进 研究技术;对现有数据集进行二次分析; 或进行离散的项目，可以证明PI的研究 能力或增加已经有价值的 应用程序. CRISP系统的其他科学数据包括 现在没空

项目成果

Steroidogenic factor 1, an orphan nuclear receptor, regulates the expression of the rat aromatase gene in gonadal tissues.

• DOI: 10.1210/mend.7.6.8395654
• 发表时间: 1993-06
• 期刊: Molecular endocrinology
• 作者: J. Lynch;D. Lala;J. Peluso;W. Luo;K. Parker;B. White

Cellular and molecular mechanisms that mediate insulin-dependent rat granulosa cell mitosis.

介导胰岛素依赖性大鼠颗粒细胞有丝分裂的细胞和分子机制。

• DOI: 10.1095/biolreprod52.1.124
• 发表时间: 1995
• 期刊: Biology of reproduction
• 影响因子: 3.6
• 作者: Peluso,JJ;Luciano,AM;Pappalardo,A;White,BA
• 通讯作者: White,BA

Effect of in vivo gonadotropin treatment on the ability of progesterone, estrogen, and cyclic adenosine 5'-monophosphate to inhibit insulin-dependent granulosa cell mitosis in vitro.

体内促性腺激素治疗对孕酮、雌激素和环腺苷 5-单磷酸体外抑制胰岛素依赖性颗粒细胞有丝分裂的能力的影响。

• DOI: 10.1095/biolreprod53.3.664
• 发表时间: 1995
• 期刊: Biology of reproduction
• 影响因子: 3.6
• 作者: Luciano,AM;Peluso,JJ
• 通讯作者: Peluso,JJ

Epidermal growth factor inhibits large granulosa cell apoptosis by stimulating progesterone synthesis and regulating the distribution of intracellular free calcium.

• DOI: 10.1095/biolreprod51.4.646
• 发表时间: 1994-10
• 期刊: Biology of reproduction
• 影响因子: 3.6
• 作者: A. M. Luciano;A. Pappalardo;C. Ray;J. Peluso