MECHANISMS OF OUABAIN-INDUCED HYPERTENSION

哇巴因诱发高血压的机制

• 批准号: 3509927
• 负责人: JOHN M HAMLYN
• 金额: $ 10万
• 依托单位: UNIVERSITY OF MARYLAND BALTIMORE
• 依托单位国家: 美国
• 财政年份: 1992
• 资助国家: 美国
• 起止时间: 1992-09-30 至 1994-09-29
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/3509927
• 关键词: cardiovascular pharmacology; hypertension; ouabain

This is a Shannon Award providing partial support for research projects that fall short of the assigned institute's funding range but are in the margin of excellence. The Shannon award is intended to provide support to test the feasibility of the approach; develop further tests and refine research techniques; perform secondary analysis of available data sets; or conduct discrete projects that can demonstrate the PI's research capabilities or lend additional weight to an already meritorious application. Further scientific data for the CRISP System are unavailable at this time.

这是香农奖，为研究项目提供部分支持 低于指定机构的资助范围但在 卓越边际。 香农奖旨在提供支持 测试该方法的可行性；进行进一步的测试并完善 研究技术；对可用数据集进行二次分析； 或开展可以展示 PI 研究成果的离散项目 能力或对已经有功绩的人给予额外的重视 应用。 CRISP 系统的更多科学数据是 目前不可用。

项目成果

Smooth muscle hypertrophy and arterial remodelling in deoxycorticosterone acetate-salt hypertension.

醋酸去氧皮质酮盐高血压中的平滑肌肥大和动脉重塑。

• DOI: 10.3109/10641969409072216
• 发表时间: 1994
• 期刊: Clinical and experimental hypertension (New York, N.Y. : 1993)
• 作者: Ashen,MD;Hamlyn,JM
• 通讯作者: Hamlyn,JM

Ouabain is secreted by bovine adrenocortical cells.

• DOI: 10.1210/endo.135.2.8033829
• 发表时间: 1994-08
• 期刊: Endocrinology
• 影响因子: 4.8
• 作者: J. Laredo;B. Hamilton;J. Hamlyn

Ouabain-induced hypertension in the rat: relationships among plasma and tissue ouabain and blood pressure.

哇巴因诱发的大鼠高血压：血浆和组织哇巴因与血压之间的关系。

• 发表时间: 1994
• 期刊: Journal of hypertension
• 影响因子: 4.9
• 作者: Manunta,P;Rogowski,AC;Hamilton,BP;Hamlyn,JM
• 通讯作者: Hamlyn,JM