A cluster RCT of the impact of a community-based hygiene and sanitation programme on infection with intestinal parasites following mass albendazole chemotherapy in Timor-Leste

一项集群随机对照试验，探讨东帝汶大规模阿苯达唑化疗后基于社区的个人卫生和环境卫生计划对肠道寄生虫感染的影响

• 批准号: nhmrc : 1013713
• 负责人: A/Pr Darren Gray
• 金额: $ 78.56万
• 依托单位: Australian National University
• 依托单位国家: 澳大利亚
• 项目类别: Partnerships
• 财政年份: 2011
• 资助国家: 澳大利亚
• 起止时间: 2011-01-01 至 2015-12-31
• 项目状态: 已结题
• 来源: https://researchdata.edu.au/cluster-rct-impact-timor-leste/109744
• 关键词: cluster; RCT; impact; community; based

Intestinal parasites cause anaemia, stunting, wasting and poor mental development in childhood, and are related to poverty and poor hygiene. Treatment with antiparasitic drugs cures infections in human hosts, but does not prevent rapid re-infection when people contact a parasite-contaminated environment. We will quantify the impact of a hygiene and sanitation programme that reduces environmental contamination in communities that receive mass treatment with the antiparasitic drug albendazole.

肠道寄生虫会导致儿童贫血、发育迟缓、消瘦和智力发育不良，并与贫困和卫生条件差有关。用抗寄生虫药物治疗可以治愈人类宿主的感染，但不能防止当人们接触被寄生虫污染的环境时迅速再次感染。我们将量化在接受抗寄生虫药物阿苯达唑大规模治疗的社区减少环境污染的卫生和环境卫生规划的影响。