SUPPORT FOR BIOMEDICAL RESEARCH

支持生物医学研究

• 批准号: 3513872
• 负责人: BOAKE L PLESSY
• 金额: $ 25.14万
• 依托单位: DILLARD UNIVERSITY
• 依托单位国家: 美国
• 财政年份: 1977
• 资助国家: 美国
• 起止时间: 1977-06-01 至 1988-12-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/3513872
• 关键词: minority institution research support

Dillard University proposes to involve three (3) faculty and nine (9) students in biomedical research projects as follows: Water Balance in the American Cockroach. Liquid scintillation counting of tritiated water used to trace water movements will be combined with column chromatography and electrophoresis of body fluids, bioassay of proteins from body fluids and electron microscopy of neurosecretory tissues to determine the role of the frontal ganglion in control of water balance in the American cockroach. Skin Testing of Fungal Antigens. Skin test reactions of patients with mycotic infections will be compared with those of "normal" populations such as nursing students and workers in nurseries and other related areas. Soil collections, cultures and inoculations into mice to delineate microfoci and to uncover the perfect stage of Sporothrix schenckii will be undertaken. Improved immunologic methods of diagnosis of fungal diseases will be sought. Characterization of Bovine Corneal Mucoproteins. Corneal Mucoproteins established as the primary contributor to hydration of the cornea will be characterized via electrophoretic fractionation. Concentration and hydration gradients will be identified in bovine corneas. The role of mucoproteins in the orderly disposition of collagen fibrils will be investigated and their role in corneal transparency ascertained.

迪拉德大学提议让三(3)名教职员工和九(9)名学生参与 在生物医学研究项目中如下：美国的水平衡 蟑螂。氚水用于示踪水的液体闪烁计数 运动将与柱层析和电泳法相结合 体液、体液中蛋白质的生物测定和电子显微镜 神经分泌组织确定额神经节在控制中的作用 美国蟑螂体内的水分平衡。真菌抗原的皮肤测试。 真菌感染患者的皮试反应将与 “正常”人群，如护生和托儿所工作人员 以及其他相关领域。土壤采集、培养和对小鼠的接种 圈定微灶，揭示申克孢子丝菌的完美发育阶段 将会被承担。真菌病免疫学诊断方法的改进 疾病将会被寻找。牛角膜粘蛋白的特性。 角膜粘蛋白是角膜水化的主要贡献者 将通过电泳法对角膜进行鉴定。浓度 水合梯度将在牛角膜中被识别出来。的作用 胶原纤维有序排列中的粘蛋白将被研究 以及它们在角膜透明度中的作用。

项目成果

A hemocoelic Candida parasite of the American cockroach (Dictyoptera: Blattidae).

美洲大蠊（网翅目：蜚蠊科）的血腔念珠菌寄生虫。

• DOI: 10.1093/jee/80.6.1205
• 发表时间: 1987
• 期刊: Journal of economic entomology
• 影响因子: 2.2
• 作者: Verrett,JM;Green,KB;Gamble,LM;Crochen,FC
• 通讯作者: Crochen,FC