VAX 11/750 COMPUTER CENTER FOR ANALYSIS OF PRIMARY DNA

这笔赠款用于购买基于VAX11/750的计算机系统 主要用于分析初级DNA、RNA和蛋白质序列数据 使用现在可用的功能强大的软件系统。该系统将包括 VAX11/750小型机、磁带机、硬盘、八道彩虹 100台微型计算机(用作智能终端)、VT241图形终端、 和打印机。在选择购买计算机系统时，我们将重点放在 对现有的软件进行了设计，使系统具有较好的兼容性。多数 在VAX计算机上运行的功能强大的程序 在VMS操作系统下(威斯康星州Devereux的U程序， 例如，斯塔登的计划和美国国立卫生研究院的代霍夫系统)。这些 程序要么是在公共领域，要么是以合理的价格提供 费用。 VAX计算机将安装在 康涅狄格大学健康中心已经运营了几个 PDP-11计算机。与调查人员的联系将通过电话进行。 计算机的操作将由一个由三人组成的小组监督 调查人员。这台机器将提供给健康中心 作为一个整体的科研人员或来自大学以外的其他人 只要机器没有被与该专业有关的工作所占用 此处描述的项目。 此应用程序中描述的系统将提供给Health 中心分子生物学社区在小学和高中的最新水平 二级序列分析计算机系统。我们一直处于截然不同的状态 没有这样一个系统的不利之处。购买此系统将 大大加强了我们的研究工作。

This grant is for the purchase of a VAX11/750 based computer system primarily for use in analyzing primary DNA, RNA and protein sequence data using the powerful software systems now available. The system will include the VAX 11/750 minicomputer, magnetic tape drive, hard disc, eight Rainbow 100 microcomputers (to act as smart terminals), VT241 graphics terminal, and printers. In choosing the computer system for purchase we have focused on the software available and designed the system to be compatible. Most of the powerful programs available operate on a VAX computer operating under the VMS operating system (Devereux's U. of Wisconsin programs, Staden's programs, and the Dayhoff system of the NIH, for example). These programs are either in the public domain or are available for a reasonable fee. The VAX computer will be housed in the Bioengineering facility of the University of Connecticut Health Center which already operates several PDP-11 computers. Connection to the investigators will be via telephone. The operation of the computer will be overseen by a group of three of the investigators. The machine will be available to the Health Center scientific staff as a whole or to others from outside the University provided that the machine is not occupied with work pertaining to the major projects described here. The system described in this application will make available to the Health Center molecular biology community the state-of-the-art in primary and secondary sequence analysis computer systems. We have been at a distinct disadvantage in not having such a system. Purchase of this system will greatly enhance our research effort.