A DIFFRACTOMETER SYSTEM FOR PROTEIN CRYSTALLOGRAPHY

蛋白质晶体学衍射仪系统

基本信息

  • 批准号:
    3519237
  • 负责人:
  • 金额:
    $ 16.46万
  • 依托单位:
  • 依托单位国家:
    美国
  • 项目类别:
  • 财政年份:
    1985
  • 资助国家:
    美国
  • 起止时间:
    1985-01-01 至 1987-09-30
  • 项目状态:
    已结题

项目摘要

Funds are requested for the purchase of an x-ray diffractometer system that will provide the primary crystallographic data for a series of interdisciplinary investigations of enzyme structure and function. Crystal structure analyses of flavodoxins, of complex flavoproteins in electron transfer chains, of flavo protein oxygenass, of Fe- and Mn- dismutases, and of Fe+3 dependent dioxygenases, conducted as an integral part of the ongoing projects of six faculty and two primary research scientists, will depend on the instrument for accurate measurements of diffracted intensities. Current and projected investigations encompass analysis of the enzymes themselves, of their complexes with substrates, products, and inhibitors, and of forms that accumulate when the reaction cycle is stopped at low temperatures. In addition, enzyme structures modified by the introduction of altered co-factors and by site-directed mutagenesis will be examined. The diffractometer system will include an x-ray generator, a four-cycle goniostat, a driver computer with accessory disks and associated software, a tape drive, a terminal, and low temperature accessories.
请拨经费购买一套x射线衍射仪系统

项目成果

期刊论文数量(1)
专著数量(0)
科研奖励数量(0)
会议论文数量(0)
专利数量(0)
Structure-function relationships in iron and manganese superoxide dismutases.
铁和锰超氧化物歧化酶的结构-功能关系。
  • DOI:
    10.3109/10715769109145794
  • 发表时间:
    1991
  • 期刊:
  • 影响因子:
    0
  • 作者:
    Stallings,WC;Metzger,AL;Pattridge,KA;Fee,JA;Ludwig,ML
  • 通讯作者:
    Ludwig,ML
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MARTHA L LUDWIG其他文献

MARTHA L LUDWIG的其他文献

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{{ truncateString('MARTHA L LUDWIG', 18)}}的其他基金

SOLUTION SCATTERING STUDIES OF CONFORMATIONS OF METHIONINE SYNTHASE
蛋氨酸合成酶构象的溶液散射研究
  • 批准号:
    7601753
  • 财政年份:
    2007
  • 资助金额:
    $ 16.46万
  • 项目类别:
SOLUTION SCATTERING STUDIES OF CONFORMATIONS OF METHIONINE SYNTHASE
蛋氨酸合成酶构象的溶液散射研究
  • 批准号:
    7369170
  • 财政年份:
    2006
  • 资助金额:
    $ 16.46万
  • 项目类别:
ANALYSIS OF CROSS LINKED COMPLEX OF THIOREDOXIN REDUCTASE & THIOREDOXIN
硫氧还蛋白还原酶交联复合物的分析
  • 批准号:
    6281284
  • 财政年份:
    1998
  • 资助金额:
    $ 16.46万
  • 项目类别:
STRUCTURE ANALYSIS OF B12 BINDING SUBUNIT OF GLUTAMATE MUTASE
谷氨酸变位酶B12结合亚基的结构分析
  • 批准号:
    6120510
  • 财政年份:
    1998
  • 资助金额:
    $ 16.46万
  • 项目类别:
ANALYSIS OF CROSS LINKED COMPLEX OF THIOREDOXIN REDUCTASE & THIOREDOXIN
硫氧还蛋白还原酶交联复合物的分析
  • 批准号:
    6120511
  • 财政年份:
    1998
  • 资助金额:
    $ 16.46万
  • 项目类别:
STRUCTURE ANALYSIS OF B12 BINDING SUBUNIT OF GLUTAMATE MUTASE
谷氨酸变位酶B12结合亚基的结构分析
  • 批准号:
    6281283
  • 财政年份:
    1998
  • 资助金额:
    $ 16.46万
  • 项目类别:
MAD STRUCTURE DETERMINATION OF METHYLENETETRAHYDROFOLATE REDUCTASE FROM E COLI
大肠杆菌亚甲基四氢叶酸还原酶的MAD结构测定
  • 批准号:
    6251640
  • 财政年份:
    1997
  • 资助金额:
    $ 16.46万
  • 项目类别:
MAD STRUCT OF GLYCEROL 3 PHOSPHATE CYTIDYLYLTRANSFERASE FROM B SUBTILIS
枯草芽孢杆菌甘油3磷酸胞苷酰基转移酶的MAD结构
  • 批准号:
    6251641
  • 财政年份:
    1997
  • 资助金额:
    $ 16.46万
  • 项目类别:
IMAGE PLATE DETECTOR FOR PROTEIN CRYSTALLOGRAPHY
用于蛋白质晶体学的图像板检测器
  • 批准号:
    2286079
  • 财政年份:
    1995
  • 资助金额:
    $ 16.46万
  • 项目类别:
MICHIGAN MOLECULAR BIOPHYSICS TRAINING PROGRAM
密歇根分子生物物理学培训计划
  • 批准号:
    6351030
  • 财政年份:
    1988
  • 资助金额:
    $ 16.46万
  • 项目类别:

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