Colon cancer and transcriptional regulation

结肠癌与转录调控

• 批准号: nhmrc : 1002117
• 负责人: Prof Robert Ramsay
• 金额: $ 53.62万
• 依托单位: The University of Melbourne
• 依托单位国家: 澳大利亚
• 项目类别: Research Fellowships
• 财政年份: 2011
• 资助国家: 澳大利亚
• 起止时间: 2011-01-01 至 2016-12-31
• 项目状态: 已结题
• 来源: https://researchdata.edu.au/colon-cancer-transcriptional-regulation/108774
• 关键词: Colon; cancer; transcriptional; regulation

Rob Ramsay has had a long standing research commitment to understanding bowel and breast cancer using mouse models with defined genetic defects. These sophisticated models replicate various stages of cancer development and some have profound effects on normal tissue biology. He also uses molecular tools to investigate how genes are controlled. These approaches are providing direct input into the development of therapeutic agents for cancer treatment.

罗布·拉姆齐长期以来一直致力于利用具有明确遗传缺陷的小鼠模型来了解肠癌和乳腺癌。这些复杂的模型复制了癌症发展的不同阶段，其中一些对正常组织生物学有深远的影响。他还使用分子工具来研究基因是如何被控制的。这些方法为癌症治疗药物的开发提供了直接的投入。