Comparative effectiveness research in childhood infections to improve decision-making in health policy and clinical practice.

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Few high quality studies of antibiotics and vaccines in children are done because they are difficult, and because there is little commercial incentive for companies to fund them. This has slowed the development of better ways to treat and prevent infections, including those which are most important for Aboriginal children. I will address this need by doing high quality studies of new treatments and vaccines in children in a way that will facilitate their rapid adoption into practice.