ADULT AIDS CLINICAL RESEARCH

成人艾滋病临床研究

• 批准号: 3791120
• 负责人: MICHAEL M LEDERMAN
• 金额: --
• 依托单位: CASE WESTERN RESERVE UNIVERSITY
• 依托单位国家: 美国
• 资助国家: 美国
• 起止时间: 至
• 项目状态: 未结题
• 来源: https://reporter.nih.gov/project-details/3791120
• 关键词: AIDS; AIDS dementia complex; AIDS therapy; HIV infections; Hispanic Americans; antiAIDS agent; brain metabolism; calcium channel blockers; clinical trials; electrophysiology; evoked potentials; female; hemophilia As; human subject; human therapy evaluation; infection related neoplasm /cancer; intravenous drug abuse; medical complication; medical outreach /case finding; microorganism disease chemotherapy; neurology; neuropsychological tests; opportunistic infections; positron emission tomography

The Case Western Reserve University AIDS Clinical Trials Unit serves a 5.4 million population region that accounts for 47% of Ohio's AIDS cases. This section provides rationale for the continuation of an established ACTU that is a vital community resource and is an important contributor to the national ACTG effort. This Cleveland and Toledo-based ACTU has a strong record of cost efficient accrual of patients including underserved minorities into ACTG trials. To provide additional trials access to minority populations, a second ACTU subunit will be established at MetroHealth Medical Center, a county hospital on Cleveland's West Side that serves large African-American and Hispanic communities. The main ACTU and its two subunits are the three largest HIV care providers in Northern Ohio and each provides care without regard to ability to pay. As both HIV care providers and AIDS researchers, these units integrate clinical care and clinical research and their staff have earned the trust and confidence of their patients and communities. Outreach to populations currently under-represented in ACTG trials is a major component of ACTU activities. These Units project a minimum accrual of 140 patients per year to ACTG trials.

凯斯西储大学艾滋病临床试验部门提供5.4 这一地区有100万人口，占俄亥俄州艾滋病病例的47%。 这 第节提供了继续建立ACTU的理由， 是一个重要的社区资源，是一个重要的贡献， 国家ACTG的努力。 这个位于克利夫兰和托莱多的ACTU在成本效益方面有着良好的记录 ACTG试验中包括服务不足的少数民族在内的患者的增加。 到 为少数群体提供额外的试验机会，第二个ACTU 将在一个县的MetroHealth医疗中心建立一个分单位 克利夫兰西区的一家医院，为非洲裔美国人和 西班牙裔社区 ACTU及其两个分单位是三个最大的艾滋病毒护理提供者 在北方俄亥俄州，每个人都提供照顾，而不考虑支付能力。 作为艾滋病毒护理提供者和艾滋病研究人员，这些单位将 临床护理和临床研究及其工作人员赢得了信任 患者和社区的信心。 与民众的外联 目前在ACTG试验中代表性不足是ACTU的主要组成部分 活动 这些单位预计每年至少增加140名患者 ACTG试验。