NEW ENGLAND PEDIATRIC ONCOLOGY CONSORTIUM

新英格兰儿科肿瘤学联盟

• 批准号: 3557063
• 负责人: EDWIN N FORMAN
• 金额: $ 8.48万
• 依托单位: RHODE ISLAND HOSPITAL
• 依托单位国家: 美国
• 财政年份: 1981
• 资助国家: 美国
• 起止时间: 1981-01-01 至 1990-12-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/3557063
• 关键词: Hodgkin's disease; asparaginase; cancer rehabilitation mental health service; child (0-11); cis platinum compound; combination cancer therapy; combination chemotherapy; cooperative study; dexamethasone; drug adverse effect; human subject; human therapy evaluation; lymphocytic leukemia; lymphoma; methotrexate; neoplasm /cancer chemotherapy; neoplasm /cancer radiation therapy; pediatric neoplasm /cancer; pediatric pharmacology; prednisone; retinoblastoma; vincristine

The objective of this project is the continued development and enhanced productivity of an efficiently functioning consortium of four New England pediatric cancer centers (Brown University/Rhode Island Hospital; Dartmouth-Hitchcock Medical Center-Norris Cotton Cancer Center; Harvard University/Massachusetts General Hospital; University of Vermont/Medical Center Hospital-Vermont Regional Cancer Center) for the purpose of: A. Contributing to the understanding and treatment of childhood malignancies through: 1. Input into national cooperative studies through active membership in the Pediatric Oncology Group (POG): a. Patient Accrual: Achieve significant number and quality of patient entries on protocols. b. Study Development and Evaluation: Assist in the development of new protocols through committee membership, institution review of proposed protocol designs, critical analysis of study results, and proposal of new protocols for POG implementation based on NEPOC studies (including identification of occult CNS leukemia through new laboratory methodology). 2. Stimulation and facilitation of cooperative efforts within NEPOC in studies of joint interest in the area of childhood malignancies, in particular toward developing potential pilot studies for POG. B. Enhancement of the care of children with cancer in the geographical areas served by the NEPOC member institutions through: 1. Assuring comprehensive and modern management of childhood malignancies as a benefit of membership in a national cooperative pediatric oncology study group; 2. Sharing the staff expertise and investigative facilities at each of the NEPOC centers; 3. Joint efforts in the promotion of education of the local community in the area of cancer in children. Through a centralized administration, this Consortium will integrate the activities and resources (staff, investigative facilities, patients) at each of the four member institutions into a single program aimed at achieving these goals.

该项目的目标是继续发展和加强 一个由四个新英格兰成员组成的高效运作的财团的生产力 儿科癌症中心（布朗大学/罗得岛医院; 达特茅斯-希区柯克医学中心-诺里斯科顿癌症中心;哈佛 大学/马萨诸塞州总医院;佛蒙特大学/医学 中心医院-佛蒙特州区域癌症中心），目的是： A.有助于理解和治疗儿童 恶性肿瘤通过： 1.通过积极参加国家合作研究， 儿科肿瘤组（POG）： a.患者累积：实现显著的患者数量和质量 协议上的条目。 B.研究开发和评估：协助开发新的 通过委员会成员资格、机构审查 方案设计，研究结果的批判性分析，以及新的 基于NEPOC研究的POG实施协议（包括 通过新实验室方法鉴定隐匿性CNS白血病）。 2.鼓励和促进非洲环境业务中心内部的合作努力， 儿童恶性肿瘤领域共同感兴趣的研究， 特别是针对POG开展潜在的试点研究。 B。加强对地区癌症儿童的护理 NEPOC成员机构通过以下方式服务的领域： 1.确保儿童恶性肿瘤的全面和现代管理 作为一个国家合作儿科肿瘤学会员的福利 学习小组; 2.在每个联合国机构分享工作人员的专门知识和调查设施， NEPOC中心; 3.共同努力，促进当地社区的教育， 儿童癌症的区域。 通过集中管理，该财团将整合 活动和资源（工作人员、调查设施、病人） 将四个成员机构中的每一个纳入一个单一的计划， 实现这些目标。