GENERAL CLINICAL RESEARCH CENTER

当前的提案要求继续支持多学科综合 临床研究中心涉及成人和儿童研究。 的 拟议的研究包括 70 多个涉及研究的独立方案 从正常人体功能的生理和生化研究， 人类疾病状态的分子病理学和病理生理学研究， 改变人类疾病状态的临床试验 治疗的实验形式和药代动力学研究，以了解 某些药物的代谢和分布。 参与调查的调查人员 研究人员包括来自内科、外科、儿科、 遗传学、药理学、精神病学、生理学、生物化学和 护理。 预计所提出的研究将带来以下方面的进展 对许多领域的正常人类功能和疾病状态的理解。 临床研究中心的持续支持将提供稳定的重点 在密歇根大学进行临床研究。 广泛的培训是 提议涉及研究员、内科住院医师、医学生、博士 细胞和分子生物学项目的候选人、护理专业的学生、 饮食学生和营养师。

The current proposal requests continuing support for a multidisciplinary general clinical research center involving research on both adults and children. The proposed research includes over 70 separate protocols which involve studies ranging from physiological and biochemical studies of normal human function, studies of the molecular pathology and pathophysiology of human disease states, clinical trials to modify human disease states with both established and experimental forms of therapy, and pharmacokinetic studies to understand the metabolism and distribution of certain drugs. The investigators involved in the research include individuals from Internal Medicine, Surgery, Pediatrics, Genetics, Pharmacology, Psychiatry, Physiology, Biological Chemistry, and Nursing. It is anticipated that the research proposed will bring advances in the understanding of normal human function and disease states in many fields. Continuing support of the Clinical Research Center will provide a stable focus for clinical research at The University of Michigan. An extensive training is proposed involving fellows, Internal Medicine residents, medical students, PhD candidates from the Cellular and Molecular Biology program, nursing students, dietetic students, and dietitians.