DEVELOP DRUGS FOR TREATMENT OF CANDIDIASIS
DEVELOP DRUGS FOR TREATMENT OF CANDIDIASIS
批准号:
3593936
负责人:
ALICE M CLARK
金额:
$16.13万
依托单位国家:
美国
项目类别:
财政年份:
1984
资助国家:
美国
项目状态:
已结题
起止时间:
1984-07-23 至 1987-07-22
关键词:
AIDS antiAIDS agent antiinfective agents candidiasis combination chemotherapy disease /disorder model dosage drug administration rate /duration drug administration routes drug adverse effect drug design /synthesis /production drug metabolism gender difference immunosuppression microorganism immunology mycosis tissue /cell culture
中文摘要
发现新的具有潜在效用的抗真菌药物
英文摘要
Discover new antifungal agents with potential utility specifically for the
treatment of disseminated Candidiasis, a common opportunistic infection in
immunocompromised individuals. This goal will be accomplished by the
initial in vitroevaluation of anti-Candidal activity of extracts of higher
plants and microorganisms. Pure antifungal compounds will beisolated with
the aid of a bioassay-directed fractionation and purification scheme. The
pure antifungal agents will be evaluated in vivo for efficacy, toxicity,
synergism, and their effect on the immune system using a mouse model of
disseminated Candidiasis.
期刊论文(4)
专著(0)
科研奖励(0)
会议论文
CHEMICAL CARCINOGEN REFERENCE STANDARD REPOSITORY
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批准号:3626315
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项目类别:
-
资助金额:$0.0万
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财政年份:1990
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负责人:ALICE M CLARK
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依托单位:
CHEMICAL CARCINOGEN REFERENCE STANDARD REPOSITORY
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批准号:3626320
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项目类别:
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资助金额:$44.03万
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财政年份:1990
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负责人:ALICE M CLARK
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依托单位:
CHEMICAL CARCINOGEN REFERENCE STANDARD REPOSITORY
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批准号:3626319
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项目类别:
-
资助金额:$20.05万
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财政年份:1990
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负责人:ALICE M CLARK
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依托单位:
CHEMICAL CARCINOGEN REFERENCE STANDARD REPOSITORY
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批准号:3626318
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项目类别:
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资助金额:$22.03万
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财政年份:1990
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负责人:ALICE M CLARK
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依托单位:
CHEMICAL CARCINOGEN REFERENCE STANDARD REPOSITORY
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批准号:3626317
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项目类别:
-
资助金额:$9.0万
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财政年份:1990
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负责人:ALICE M CLARK
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依托单位:
DEVELOP DRUGS FOR TREATMENT OF CANDIDIASIS
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批准号:3596032
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项目类别:
-
资助金额:$0.0万
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财政年份:1987
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负责人:ALICE M CLARK
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依托单位:
DEVELOP DRUGS FOR TREATMENT OF CANDIDIASIS
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批准号:3596030
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项目类别:
-
资助金额:$21.98万
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财政年份:1987
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负责人:ALICE M CLARK
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依托单位:
DEVELOP DRUGS FOR TREATMENT OF CANDIDIASIS
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批准号:3596028
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项目类别:
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资助金额:$0.0万
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财政年份:1987
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负责人:ALICE M CLARK
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依托单位:
DEVELOP DRUGS FOR TREATMENT OF CANDIDIASIS
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批准号:3596031
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项目类别:
-
资助金额:$22.8万
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财政年份:1987
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负责人:ALICE M CLARK
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依托单位:
DEVELOP DRUGS FOR TREATMENT OF CANDIDIASIS
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批准号:3596025
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项目类别:
-
资助金额:$20.53万
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财政年份:1987
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负责人:ALICE M CLARK
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依托单位:
DEVELOP DRUGS FOR TREATMENT OF CANDIDIASIS
-
批准号:3596024
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项目类别:
-
资助金额:$20.06万
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财政年份:1987
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负责人:ALICE M CLARK
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依托单位:
DEVELOP DRUGS FOR TREATMENT OF CANDIDIASIS
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批准号:3596029
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项目类别:
-
资助金额:$21.29万
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财政年份:1987
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负责人:ALICE M CLARK
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依托单位:
DEVELOP DRUGS FOR TREATMENT OF CANDIDIASIS
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批准号:3593934
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项目类别:
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资助金额:$14.87万
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财政年份:1984
-
负责人:ALICE M CLARK
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依托单位:
DEVELOP DRUGS FOR TREATMENT OF CANDIDIASIS
-
批准号:3593932
-
项目类别:
-
资助金额:$0.0万
-
财政年份:1984
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负责人:ALICE M CLARK
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依托单位:
海外基金