ACADEMIC NURSING HOME

约翰霍普金斯大学疗养院(JHANH)代表着一种特殊的 针对与之相关的现象和问题的项目 人类过度肥胖与衰老之间的相互作用 鼓励、审查、协调和促进的机制 对与人类老龄化相关的问题进行补充研究。当居中时 巴尔的摩市医院(BCH)校园内的机构(Mason F. 洛德[MFL]巴尔的摩慢性医院和熟练的护理设施 市医院和国家老年医学研究中心 老龄化研究所)，JHANH将利用广泛的人类和 约翰霍普金斯大学医疗机构的非人力资源， 值得注意的是医学院，学校和卫生与公共卫生， 和(1984年重新启用)护理学院。核心设施 将提供行政、科学咨询和审查职能，以及 具有生物统计学咨询专业知识的患者登记和 将所有研究对象纳入老龄化-肥胖项目的机制， 主要BCH初级保健医生执业的患者，患者 MFL和参加老年居民流行病学调查的受试者 巴尔的摩东南部社区的成员。由核心推动的先导研究 包括那些针对详细描述地球生命的自然历史的文章 MFL和新入住该设施的患者的康复。这个 四个具体项目代表了一种紧密集成的方法，以 代谢调节、心肺生理学等复杂现象 (强调锻炼和热量调节)，睡眠生理学，以及 神经心理功能。在这个多方面的项目中，无烟 三个年龄段(45-49岁、60-74岁和75岁及以上)的肥胖男性受试者 将接受这四个领域的基线评估，随后 他们将被随机分配到观察对照，通过 低热量疗法，或耐力有氧运动训练。12点以后。 月，这些评估将重复进行，受试者将重新分配到 观察状态，36个月后再次进行评估 最初进入这项研究。因此，这项研究将解决这些问题 与数量有关(通过肥胖对 心血管风险概况)和质量(通过睡眠和相关 西方社会老年人生活中的神经心理障碍 其中过度肥胖是如此普遍。

The Johns Hopkins Academic Nursing Home (JHANH) represents both a specific program project directed toward phenomena and problems related to the interaction between excess adiposity and aging in the human and also a mechanism for encouraging, reviewing, coordinating, and facilitating additional research on problems relevant to human aging. While centered in the institutions on the Baltimore City Hospitals (BCH) campus (the Mason F. Lord [MFL] chronic hospital and skilled nursing facility, the Baltimore City Hospital, and the Gerontology Research Center of the National Institute on Aging), the JHANH will capitalize upon the extensive human and non-human resources of the Johns Hopkins Medical Institutions at large, notably the School of Medicine, the School and Hygiene and Public Health, and (when re-activated in 1984) the School of Nursing. The core facility will provide administration, scientific advisory and review functions, and a patient registry with biostatistical consultative expertise and the mechanism to enroll all study subjects in the aging-adiposity projects, patients in the practices of key BCH primary care physicians, patients in MFL, and subjects enrolled in an epidemiologic survey of elderly residents of the Southeast Baltimore community. Pilot studies promoted by the core include those directed toward detailing the natural history of life in the MFL and rehabilitation of patients newly admitted to that facility. The four specific projects represent a tightly-integrated approach to the complex phenomena of metabolic regulation, cardiopulmonary physiology (emphasizing exercise and heat regulation), sleep physiology, and neuropsychological function. In this multi-faceted project non-smoking obese male subjects of three age groups (45-49, 60-74, and 75 and older) will receive baseline evaluations in these four spheres, following which they will be randomly assigned to observation-control, weight loss through hypocaloric therapy, or endurance aerobic exercise training. After twelve months these assessments will be repeated, the subject re-assigned to observational status, and assessment repeated once again 36 months after initial entry into the study. Thus this research will address problems related both to the quantity (via the central effects of obesity upon cardiovascular risk profiles) and quality (via sleep and related neuropsychological disturbances) of life of aging man in Occidental society in which excess adiposity is so prevalent.