Contribution of systemic inflammatory response to brain injury in growth restricted newborns

全身炎症反应对生长受限新生儿脑损伤的影响

• 批准号: nhmrc : GNT1147545
• 负责人: Dr Julie Wixey
• 金额: $ 35.84万
• 依托单位国家: 澳大利亚
• 项目类别: Project Grants
• 财政年份: 2018
• 资助国家: 澳大利亚
• 起止时间: 2018-01-01 至 无数据
• 项目状态: 已结题
• 来源: https://researchdata.edu.au/contribution-systemic-inflammatory-restricted-newborns/1348832
• 关键词: Contribution; systemic; inflammatory; response; brain

Growth restriction during pregnancy can damage the baby’s brain and result in poor outcomes such as learning and attention difficulties and cerebral palsy. Currently there is no treatment available to prevent brain injury in these babies. This study will explore the role of inflammation and brain injury in the growth restricted baby. We will also examine whether a readily available and safe anti-inflammatory treatment can reduce or prevent brain injury following growth restriction.

怀孕期间的生长受限会损害婴儿的大脑，并导致学习和注意力障碍以及脑瘫等不良结局。目前还没有可用的治疗方法来预防这些婴儿的脑损伤。本研究将探讨炎症和脑损伤在生长受限婴儿中的作用。我们还将研究一种现成的、安全的抗炎治疗是否可以减少或预防生长受限后的脑损伤。